Annotations: 4YTD

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	BicD coiled coil region-like	8045490	4004493	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	BicD coiled coil region-like	8090809	3002456	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	BicD coiled coil region-like	8090809	3002456	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF09730	Microtubule-associated protein Bicaudal-D (BicD)	Microtubule-associated protein Bicaudal-D	-	Coiled-coil

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Protein bicaudal D homolog 1	small GTPase binding protein binding binding enzyme binding GTPase binding proteinase activated receptor binding signaling receptor binding G protein-coupled receptor binding kinase binding protein kinase binding protein-macromolecule adaptor activity cytoskeletal anchor activity molecular adaptor activity cytoskeletal protein binding small GTPase binding protein binding binding enzyme binding GTPase binding proteinase activated receptor binding signaling receptor binding G protein-coupled receptor binding kinase binding protein kinase binding protein-macromolecule adaptor activity cytoskeletal anchor activity molecular adaptor activity cytoskeletal protein binding dynactin binding dynein intermediate chain binding protein-containing complex binding dynein complex binding	viral process cellular component organization organelle organization microtubule anchoring at microtubule organizing center microtubule cytoskeleton organization cellular process microtubule-based process cellular component organization or biogenesis microtubule anchoring cytoskeleton organization protein localization localization cellular localization protein localization to organelle viral process cellular component organization organelle organization microtubule anchoring at microtubule organizing center microtubule cytoskeleton organization cellular process microtubule-based process cellular component organization or biogenesis microtubule anchoring cytoskeleton organization protein localization localization cellular localization protein localization to organelle cellular macromolecule localization macromolecule localization establishment of organelle localization organelle transport along microtubule transport intracellular transport establishment of localization minus-end-directed organelle transport along microtubule organelle localization establishment of localization in cell microtubule-based transport transport along microtubule cytoskeleton-dependent intracellular transport microtubule-based movement regulation of cytoskeleton organization regulation of biological process regulation of cellular component organization regulation of cellular process biological regulation regulation of microtubule-based process regulation of organelle organization regulation of microtubule cytoskeleton organization regulation of phospholipase activity negative regulation of hydrolase activity regulation of catalytic activity negative regulation of lipase activity negative regulation of molecular function negative regulation of catalytic activity negative regulation of phospholipase C activity negative regulation of phospholipase activity regulation of molecular function regulation of phospholipase C activity regulation of hydrolase activity regulation of lipase activity regulation of localization import into cell positive regulation of cellular component organization positive regulation of biological process vesicle-mediated transport positive regulation of endocytosis positive regulation of receptor-mediated endocytosis positive regulation of cellular process regulation of endocytosis regulation of transport regulation of receptor-mediated endocytosis regulation of vesicle-mediated transport positive regulation of transport endocytosis receptor-mediated endocytosis cellular component biogenesis cellular component assembly stress granule assembly organelle assembly non-membrane-bounded organelle assembly protein localization to microtubule cytoskeleton regulation of protein localization regulation of protein localization to centrosome protein localization to microtubule organizing center regulation of cellular localization protein localization to cytoskeleton positive regulation of protein localization positive regulation of protein localization to centrosome protein localization to centrosome cellular response to stimulus response to stimulus signaling negative regulation of signaling negative regulation of biological process regulation of signal transduction negative regulation of G protein-coupled receptor signaling pathway negative regulation of cell communication phospholipase C-activating G protein-coupled receptor signaling pathway cell communication negative regulation of cellular process signal transduction regulation of G protein-coupled receptor signaling pathway regulation of signaling negative regulation of response to stimulus negative regulation of signal transduction regulation of response to stimulus regulation of cell communication G protein-coupled receptor signaling pathway negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway regulation of phospholipase C-activating G protein-coupled receptor signaling pathway regulation of signaling receptor activity regulation of proteinase activated receptor activity	membrane cellular anatomical entity intracellular organelle centrosome microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle microtubule cytoskeleton non-membrane-bounded organelle cytoplasm cytosol membrane-bounded organelle membrane cellular anatomical entity intracellular organelle centrosome microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle microtubule cytoskeleton non-membrane-bounded organelle cytoplasm cytosol membrane-bounded organelle cytoplasmic vesicle intracellular vesicle intracellular membrane-bounded organelle vesicle Golgi apparatus subcompartment Golgi apparatus organelle subcompartment endomembrane system trans-Golgi network secretory vesicle perinuclear region of cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR018477	Bicaudal-D protein	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.