Annotations: 4Y7L

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF06744	e4y7lA2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: C2 domain (From Topology)	T: C2 domain	F: PF06744	ECOD (1.6)
A	PF21070	e4y7lA1	A: alpha bundles	X: Four-helical up-and-down bundle	H: Type VI secretion protein IcmF helical domain (From Topology)	T: Type VI secretion protein IcmF helical domain	F: PF21070	ECOD (1.6)
B	PF06744	e4y7lB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: C2 domain (From Topology)	T: C2 domain	F: PF06744	ECOD (1.6)
B	PF21070	e4y7lB2	A: alpha bundles	X: Four-helical up-and-down bundle	H: Type VI secretion protein IcmF helical domain (From Topology)	T: Type VI secretion protein IcmF helical domain	F: PF21070	ECOD (1.6)

Chains	Accession	Name	Description	Comments	Source
A, B	PF06744	Type VI secretion protein IcmF C2-like domain (IcmF_C)	Type VI secretion protein IcmF C2-like domain	IcmF_C family represents a conserved region situated towards the C-terminal end of IcmF-like proteins. It was thought to be involved in Vibrio cholerae cell surface reorganisation that results in increased adherence to epithelial cells leading to an ...	IcmF_C family represents a conserved region situated towards the C-terminal end of IcmF-like proteins. It was thought to be involved in Vibrio cholerae cell surface reorganisation that results in increased adherence to epithelial cells leading to an increased conjugation frequency [1]. IcmF as a whole interacts with DotU whereby these bind tightly and form the docking area of the T6SS within the inner membrane. The exact function of this domain is not clear [2].	Domain
A, B	PF21070	Type VI secretion protein IcmF helical domain (IcmF_helical)	Type VI secretion protein IcmF helical domain	This entry represents the alpha-helical domain from the Type VI secretion protein IcmF [1]. This domain is also found in the TssM protein where it forms part of the tip complex [1].	Domain