4XI8

Crystal Structure of the FIC domain of Bep5 protein (VirB-translocated Bartonella effector protein) from Bartonella clarridgeiae

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Fic-like	8101413	3001922	SCOP2B (2022-06-29)
B	SCOP2 Family	Fic-like	8101412	4001592	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Fic-like	8101413	3001922	SCOP2 (2022-06-29)
C	SCOP2B Superfamily	Fic-like	8101413	3001922	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Fic-like	8101413	3001922	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Fic-like	8101413	3001922	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02661	e4xi8A1	A: alpha bundles	X: Fic-like (From Topology)	H: Fic-like (From Topology)	T: Fic-like	F: PF02661	ECOD (1.6)
B	PF02661	e4xi8B1	A: alpha bundles	X: Fic-like (From Topology)	H: Fic-like (From Topology)	T: Fic-like	F: PF02661	ECOD (1.6)
C	PF02661	e4xi8C1	A: alpha bundles	X: Fic-like (From Topology)	H: Fic-like (From Topology)	T: Fic-like	F: PF02661	ECOD (1.6)
D	PF02661	e4xi8D1	A: alpha bundles	X: Fic-like (From Topology)	H: Fic-like (From Topology)	T: Fic-like	F: PF02661	ECOD (1.6)
E	PF02661	e4xi8E1	A: alpha bundles	X: Fic-like (From Topology)	H: Fic-like (From Topology)	T: Fic-like	F: PF02661	ECOD (1.6)
F	PF02661	e4xi8F1	A: alpha bundles	X: Fic-like (From Topology)	H: Fic-like (From Topology)	T: Fic-like	F: PF02661	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.3290.10	Mainly Alpha	Orthogonal Bundle	Fic-like fold	Fido-like domain	CATH (4.3.0)
B	1.10.3290.10	Mainly Alpha	Orthogonal Bundle	Fic-like fold	Fido-like domain	CATH (4.3.0)
C	1.10.3290.10	Mainly Alpha	Orthogonal Bundle	Fic-like fold	Fido-like domain	CATH (4.3.0)
D	1.10.3290.10	Mainly Alpha	Orthogonal Bundle	Fic-like fold	Fido-like domain	CATH (4.3.0)
E	1.10.3290.10	Mainly Alpha	Orthogonal Bundle	Fic-like fold	Fido-like domain	CATH (4.3.0)
F	1.10.3290.10	Mainly Alpha	Orthogonal Bundle	Fic-like fold	Fido-like domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF02661	Fic/DOC family (Fic)	Fic/DOC family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Bartonella effector protein (Bep) substrate of VirB T4SS	transferase activity catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR036597	Fido-like domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR040548	BepA, intracellular delivery domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR003812	Fido domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.