4V1W

3D structure of horse spleen apoferritin determined by electron cryomicroscopy

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
P	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
Q	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
S	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
T	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
U	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
W	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
X	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
O	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
R	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)
V	SCOP2B Superfamily	Ferritin-like	8037855	3001658	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00210	e4v1wA1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
B	PF00210	e4v1wB1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
C	PF00210	e4v1wC1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
D	PF00210	e4v1wD1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
F	PF00210	e4v1wF1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
H	PF00210	e4v1wH1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
I	PF00210	e4v1wI1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
J	PF00210	e4v1wJ1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
K	PF00210	e4v1wK1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
L	PF00210	e4v1wL1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
M	PF00210	e4v1wM1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
N	PF00210	e4v1wN1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
P	PF00210	e4v1wP1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
Q	PF00210	e4v1wQ1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
S	PF00210	e4v1wS1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
T	PF00210	e4v1wT1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
U	PF00210	e4v1wU1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
W	PF00210	e4v1wW1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
X	PF00210	e4v1wX1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
E	PF00210	e4v1wE1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
G	PF00210	e4v1wG1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
O	PF00210	e4v1wO1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
R	PF00210	e4v1wR1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)
V	PF00210	e4v1wV1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: PF00210	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X	PF00210	Ferritin-like domain (Ferritin)	Ferritin-like domain	This family contains ferritins and other ferritin-like proteins such as members of the DPS family and bacterioferritins.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X	FERRITIN LIGHT CHAIN	cation binding transition metal ion binding iron ion binding ion binding binding ferrous iron binding metal ion binding small molecule binding ferric iron binding	localization transport iron ion transport transition metal ion transport monoatomic ion transport monoatomic cation transport establishment of localization metal ion transport cellular localization inorganic ion homeostasis homeostatic process sequestering of metal ion maintenance of location in cell maintenance of location localization transport iron ion transport transition metal ion transport monoatomic ion transport monoatomic cation transport establishment of localization metal ion transport cellular localization inorganic ion homeostasis homeostatic process sequestering of metal ion maintenance of location in cell maintenance of location intracellular iron ion homeostasis cellular homeostasis chemical homeostasis sequestering of iron ion intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis cellular process intracellular sequestering of iron ion monoatomic cation homeostasis intracellular monoatomic ion homeostasis	ferritin complex protein-containing complex intracellular ferritin complex intracellular protein-containing complex intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X	IPR009040	Ferritin-like diiron domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X	IPR012347	Ferritin-like	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X	IPR009078	Ferritin-like superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X	IPR001519	Ferritin	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X	IPR014034	Ferritin, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X	IPR008331	Ferritin/DPS protein domain	Domain