4UU4

Crystal structure of LptH, the LptA homologous periplasmic component of the conserved lipopolysaccharide transport device from Pseudomonas aeruginosa

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	LptA-like	8045265	4004381	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	OstA-like beta-folder	8053501	3002196	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF03968	e4uu4A1	A: beta meanders	X: Periplasmic lipopolysaccharide transport protein LptA (YhbN) (From Topology)	H: Periplasmic lipopolysaccharide transport protein LptA (YhbN) (From Topology)	T: Periplasmic lipopolysaccharide transport protein LptA (YhbN)	F: PF03968	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.450.10	Mainly Beta	Sandwich	lipopolysaccharide transport protein A fold	Lipopolysaccharide (LPS) transport protein A like domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF03968	LptA/(LptD N-terminal domain) LPS transport protein (LptD_N)	LptA/(LptD N-terminal domain) LPS transport protein	This family of proteins are involved in lipopolysaccharide transport across the gram negative inner and outer membranes. The type examples for this family are E. coli LptA Swiss:P0ADV1 and the N-terminal domain of LptD Swiss:P31554.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	PERIPLASMIC LIPOPOLYSACCHARIDE TRANSPORT PROTEIN LPTH	lipid transporter activity lipid transfer activity transporter activity glycolipid transfer activity binding lipid binding lipopolysaccharide binding carbohydrate derivative binding	membrane organization membrane biogenesis membrane assembly cellular component organization cellular component biogenesis cellular component assembly cellular process cellular component organization or biogenesis cell envelope organization Gram-negative-bacterium-type cell outer membrane assembly external encapsulating structure organization localization transport lipopolysaccharide transport membrane organization membrane biogenesis membrane assembly cellular component organization cellular component biogenesis cellular component assembly cellular process cellular component organization or biogenesis cell envelope organization Gram-negative-bacterium-type cell outer membrane assembly external encapsulating structure organization localization transport lipopolysaccharide transport macromolecule localization organic substance transport lipid localization lipid transport carbohydrate derivative transport establishment of localization	outer membrane-bounded periplasmic space cell envelope periplasmic space cellular anatomical entity cell periphery cell outer membrane external encapsulating structure membrane outer membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR014340	Lipopolysaccharide export system protein LptA	Family
A	IPR005653	Organic solvent tolerance-like, N-terminal	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.