4UJC

mammalian 80S HCV-IRES initiation complex with eIF5B POST-like state

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B [auth AB]	PF03144	e4ujcAB4	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF03144	ECOD (1.6)
B [auth AB]	PF14578	e4ujcAB1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF14578	ECOD (1.6)
B [auth AB]	PF00009	e4ujcAB3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00009	ECOD (1.6)
B [auth AB]	PF11987	e4ujcAB2	A: a/b three-layered sandwiches	X: Initiation factor IF2/eIF5b, domain 3 (From Topology)	H: Initiation factor IF2/eIF5b, domain 3 (From Topology)	T: Initiation factor IF2/eIF5b, domain 3	F: PF11987	ECOD (1.6)
G [auth BA]	PF00181	e4ujcBA1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF00181	ECOD (1.6)
G [auth BA]	PF03947	e4ujcBA2	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF03947	ECOD (1.6)
H [auth BB]	PF00297	e4ujcBB1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF00297	ECOD (1.6)
I [auth BC]	PF00573	e4ujcBC2	A: a/b three-layered sandwiches	X: Ribosomal protein L4 (From Topology)	H: Ribosomal protein L4 (From Topology)	T: Ribosomal protein L4	F: PF00573	ECOD (1.6)
I [auth BC]	PF14374	e4ujcBC1	A: extended segments	X: C-terminal helical region in 60S ribosomal protein L4 (L4p) (From Topology)	H: C-terminal helical region in 60S ribosomal protein L4 (L4p) (From Topology)	T: C-terminal helical region in 60S ribosomal protein L4 (L4p)	F: PF14374	ECOD (1.6)
J [auth BD]	PF14204,PF17144	e4ujcBD1	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF14204,PF17144	ECOD (1.6)
K [auth BE]	PF01159	e4ujcBE1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01159	ECOD (1.6)
L [auth BF]	PF00327,PF08079	e4ujcBF1	A: a+b two layers	X: Ribosomal protein L30p/L7e (From Topology)	H: Ribosomal protein L30p/L7e (From Topology)	T: Ribosomal protein L30p/L7e	F: PF00327,PF08079	ECOD (1.6)
M [auth BG]	PF01248	e4ujcBG1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: L30e-like (From Topology)	T: L30e-like	F: PF01248	ECOD (1.6)
N [auth BH]	PF00347	e4ujcBH1	A: a+b two layers	X: Ribosomal protein L6 (From Topology)	H: Ribosomal protein L6 (From Topology)	T: Ribosomal protein L6	F: PF00347	ECOD (1.6)
O [auth BI]	PF00252	e4ujcBI1	A: a+b complex topology	X: alpha/beta-Hammerhead/Barrel-sandwich hybrid	H: alpha/beta-Hammerhead/Barrel-sandwich hybrid	T: Ribosomal protein L10e	F: PF00252	ECOD (1.6)
P [auth BJ]	PF00281,PF00673	e4ujcBJ1	A: a+b two layers	X: Ribosomal protein L5 (From Topology)	H: Ribosomal protein L5 (From Topology)	T: Ribosomal protein L5	F: PF00281,PF00673	ECOD (1.6)
Q [auth BL]	PF01294	e4ujcBL1	A: extended segments	X: RPL13 (From Topology)	H: RPL13 (From Topology)	T: RPL13	F: PF01294	ECOD (1.6)
R [auth BM]	PF00467,PF01929	e4ujcBM1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF00467,PF01929	ECOD (1.6)
S [auth BN]	PF00827	e4ujcBN1	A: a+b two layers	X: Alpha-beta plaits	H: Ribosomal proteins S24e, L23 and L15e (From Topology)	T: Ribosomal proteins S24e, L23 and L15e	F: PF00827	ECOD (1.6)
T [auth BO]	PF00572	e4ujcBO1	A: a/b three-layered sandwiches	X: Ribosomal protein L13/L15p/L18e/L32e	H: Ribosomal protein L13 and L16-A (From Topology)	T: Ribosomal protein L13 and L16-A	F: PF00572	ECOD (1.6)
U [auth BP]	PF00237	e4ujcBP1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Ribosomal protein L22 (From Topology)	T: Ribosomal protein L22	F: PF00237	ECOD (1.6)
V [auth BQ]	PF17135	e4ujcBQ1	A: a/b three-layered sandwiches	X: Ribosomal protein L13/L15p/L18e/L32e	H: Ribosomal proteins L15p and L18e (From Topology)	T: Ribosomal proteins L15p and L18e	F: PF17135	ECOD (1.6)
W [auth BR]	PF01280	e4ujcBR2	A: alpha arrays	X: Ribosomal protein L19 (L19e) N-terminal domain (From Topology)	H: Ribosomal protein L19 (L19e) N-terminal domain (From Topology)	T: Ribosomal protein L19 (L19e) N-terminal domain	F: PF01280	ECOD (1.6)
W [auth BR]	PF01280	e4ujcBR1	A: alpha bundles	X: Ribosomal protein L19 (L19e) C-terminal domain (From Topology)	H: Ribosomal protein L19 (L19e) C-terminal domain (From Topology)	T: Ribosomal protein L19 (L19e) C-terminal domain	F: PF01280	ECOD (1.6)
X [auth BS]	F_UNCLASSIFIED	e4ujcBS1	A: a+b two layers	X: GP2-like	H: RplX-like (From Topology)	T: RplX-like	F: F_UNCLASSIFIED	ECOD (1.6)
X [auth BS]	PF01775	e4ujcBS2	A: a+b two layers	X: GP2-like	H: RplX-like (From Topology)	T: RplX-like	F: PF01775	ECOD (1.6)
Y [auth BT]	PF01157	e4ujcBT1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01157	ECOD (1.6)
Z [auth BU]	PF01776	e4ujcBU1	A: a+b two layers	X: Ribosomal protein L22e (From Topology)	H: Ribosomal protein L22e (From Topology)	T: Ribosomal protein L22e	F: PF01776	ECOD (1.6)
AA [auth BV]	PF00238	e4ujcBV1	A: beta barrels	X: Ribosomal protein L14-like	H: Ribosomal protein L14-related (From Topology)	T: Ribosomal protein L14-related	F: PF00238	ECOD (1.6)
BA [auth BW]	PF01246	e4ujcBW1	A: few secondary structure elements	X: Glucocorticoid receptor-like	H: LIM domain-like	T: LIM domain-like	F: PF01246	ECOD (1.6)
DA [auth BY]	PF16906	e4ujcBY1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF16906	ECOD (1.6)
EA [auth BZ]	PF00467,PF01777	e4ujcBZ1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF00467,PF01777	ECOD (1.6)
FA [auth Ba]	PF00828	e4ujcBa1	A: a/b three-layered sandwiches	X: Ribosomal protein L13/L15p/L18e/L32e	H: Ribosomal proteins L15p and L18e (From Topology)	T: Ribosomal proteins L15p and L18e	F: PF00828	ECOD (1.6)
GA [auth Bb]	PF01779	e4ujcBb1	A: extended segments	X: RPL29 (From Topology)	H: RPL29 (From Topology)	T: RPL29	F: PF01779	ECOD (1.6)
HA [auth Bc]	PF01248	e4ujcBc1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: L30e-like (From Topology)	T: L30e-like	F: PF01248	ECOD (1.6)
IA [auth Bd]	PF01198	e4ujcBd1	A: a+b two layers	X: Ribosomal protein L31e-like	H: Ribosomal protein L31e/gp120 outer domain (From Topology)	T: Ribosomal protein L31e/gp120 outer domain	F: PF01198	ECOD (1.6)
JA [auth Be]	PF01655	e4ujcBe1	A: a/b three-layered sandwiches	X: Ribosomal protein L13/L15p/L18e/L32e	H: Ribosomal protein L32e (From Topology)	T: Ribosomal protein L32e	F: PF01655	ECOD (1.6)
KA [auth Bf]	PF01247	e4ujcBf1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF01247	ECOD (1.6)
LA [auth Bg]	PF01199	e4ujcBg1	A: few secondary structure elements	X: Glucocorticoid receptor-like	H: RPL34 (From Topology)	T: RPL34	F: PF01199	ECOD (1.6)
MA [auth Bh]	PF00831	e4ujcBh1	A: alpha bundles	X: Long alpha-hairpin	H: Ribosomal protein L29 (L29p) (From Topology)	T: Ribosomal protein L29 (L29p)	F: PF00831	ECOD (1.6)
NA [auth Bi]	PF01158	e4ujcBi1	A: alpha arrays	X: 60S ribosomal protein rpL36 (L36e) (From Topology)	H: 60S ribosomal protein rpL36 (L36e) (From Topology)	T: 60S ribosomal protein rpL36 (L36e)	F: PF01158	ECOD (1.6)
OA [auth Bj]	PF01907	e4ujcBj1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF01907	ECOD (1.6)
PA [auth Bk]	PF01781	e4ujcBk1	A: a+b two layers	X: SRP9/14-like	H: Signal recognition particle alu RNA binding heterodimer SRP9/14-related (From Topology)	T: Signal recognition particle alu RNA binding heterodimer SRP9/14-related	F: PF01781	ECOD (1.6)
QA [auth Bl]	PF00832	e4ujcBl1	A: extended segments	X: Ribosomal protein L39e (From Topology)	H: Ribosomal protein L39e (From Topology)	T: Ribosomal protein L39e	F: PF00832	ECOD (1.6)
RA [auth Bm]	PF01020	e4ujcBm1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF01020	ECOD (1.6)
SA [auth Bn]	PF05162	e4ujcBn1	A: extended segments	X: Ribosomal protein L41-A (From Topology)	H: Ribosomal protein L41-A (From Topology)	T: Ribosomal protein L41-A	F: PF05162	ECOD (1.6)
TA [auth Bo]	PF00935	e4ujcBo1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF00935	ECOD (1.6)
UA [auth Bp]	PF01780	e4ujcBp1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF01780	ECOD (1.6)
VA [auth Bt]	PF01778	e4ujcBt1	A: a+b two layers	X: RPL28 (From Topology)	H: RPL28 (From Topology)	T: RPL28	F: PF01778	ECOD (1.6)
WA [auth Bu]	PF00687	e4ujcBu1	A: a+b two layers	X: a+b domain in Ribosomal protein L1 (From Topology)	H: a+b domain in Ribosomal protein L1 (From Topology)	T: a+b domain in Ribosomal protein L1	F: PF00687	ECOD (1.6)
WA [auth Bu]	PF00687	e4ujcBu2	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Rossmann-like domain in Ribosomal protein L1 (From Topology)	T: Rossmann-like domain in Ribosomal protein L1	F: PF00687	ECOD (1.6)
YA [auth CA]	PF00318	e4ujcCA1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Ribosomal protein S2/SIS domain (From Topology)	T: Ribosomal protein S2/SIS domain	F: PF00318	ECOD (1.6)
ZA [auth CB]	PF01015	e4ujcCB2	A: beta barrels	X: Ribosomal protein L25-like	H: 40S ribosomal protein S3A N-terminal domain (From Topology)	T: 40S ribosomal protein S3A N-terminal domain	F: PF01015	ECOD (1.6)
ZA [auth CB]	PF01015	e4ujcCB1	A: a+b two layers	X: T-fold	H: 40S ribosomal protein S3A C-terminal domain (From Topology)	T: 40S ribosomal protein S3A C-terminal domain	F: PF01015	ECOD (1.6)
AB [auth CC]	PF03719	e4ujcCC2	A: a+b two layers	X: Ribosomal protein S5 domain 2-like (From Topology)	H: Ribosomal protein S5 domain 2-like (From Topology)	T: Ribosomal protein S5 domain 2-like	F: PF03719	ECOD (1.6)
AB [auth CC]	PF00333	e4ujcCC3	A: a+b two layers	X: dsRBD-like	H: dsRNA-binding domain-like (From Topology)	T: dsRNA-binding domain-like	F: PF00333	ECOD (1.6)
AB [auth CC]	PF00333	e4ujcCC1	A: extended segments	X: N-terminal region in 40S ribosomal protein rpS2 (S5p) (From Topology)	H: N-terminal region in 40S ribosomal protein rpS2 (S5p) (From Topology)	T: N-terminal region in 40S ribosomal protein rpS2 (S5p)	F: PF00333	ECOD (1.6)
CB [auth CE]	PF00900	e4ujcCE3	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF00900	ECOD (1.6)
CB [auth CE]	PF00467,PF16121	e4ujcCE1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF00467,PF16121	ECOD (1.6)
CB [auth CE]	PF00900,PF08071	e4ujcCE2	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Alpha-L RNA-binding motif	F: PF00900,PF08071	ECOD (1.6)
DB [auth CF]	PF00177	e4ujcCF1	A: alpha arrays	X: Ribosomal protein S7 (From Topology)	H: Ribosomal protein S7 (From Topology)	T: Ribosomal protein S7	F: PF00177	ECOD (1.6)
EB [auth CG]	PF01092	e4ujcCG1	A: beta barrels	X: Ribosomal protein L25-like	H: Ribosomal protein L25-like (From Topology)	T: Ribosomal protein L25-like	F: PF01092	ECOD (1.6)
FB [auth CH]	PF01251	e4ujcCH2	A: a+b two layers	X: Alpha-lytic protease prodomain-like	H: 40S ribosomal protein S7-A (From Topology)	T: 40S ribosomal protein S7-A	F: PF01251	ECOD (1.6)
HB [auth CJ]	PF00163,PF01479	e4ujcCJ1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Alpha-L RNA-binding motif	F: PF00163,PF01479	ECOD (1.6)
JB [auth CL]	PF00366,PF16205	e4ujcCL1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF00366,PF16205	ECOD (1.6)
KB [auth CM]	PF01248	e4ujcCM1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: L30e-like (From Topology)	T: L30e-like	F: PF01248	ECOD (1.6)
LB [auth CN]	PF08069	e4ujcCN2	A: alpha arrays	X: HTH	H: 40S ribosomal protein S13 N-terminal domain (From Topology)	T: 40S ribosomal protein S13 N-terminal domain	F: PF08069	ECOD (1.6)
LB [auth CN]	PF00312	e4ujcCN1	A: alpha arrays	X: S15/NS1 RNA-binding domain (From Topology)	H: S15/NS1 RNA-binding domain (From Topology)	T: S15/NS1 RNA-binding domain	F: PF00312	ECOD (1.6)
MB [auth CO]	PF00411	e4ujcCO1	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00411	ECOD (1.6)
NB [auth CP]	PF00203	e4ujcCP1	A: a+b two layers	X: Ribosomal protein S19 (From Topology)	H: Ribosomal protein S19 (From Topology)	T: Ribosomal protein S19	F: PF00203	ECOD (1.6)
OB [auth CQ]	PF00380	e4ujcCQ1	A: a+b two layers	X: Ribosomal protein S5 domain 2-like (From Topology)	H: Ribosomal protein S5 domain 2-like (From Topology)	T: Ribosomal protein S5 domain 2-like	F: PF00380	ECOD (1.6)
PB [auth CR]	PF00833	e4ujcCR1	A: alpha arrays	X: HTH	H: HTH	T: FF domain	F: PF00833	ECOD (1.6)
QB [auth CS]	PF00416	e4ujcCS1	A: alpha arrays	X: HhH/H2TH	H: H2TH (From Topology)	T: H2TH	F: PF00416	ECOD (1.6)
RB [auth CT]	PF01090	e4ujcCT1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: PF01090	ECOD (1.6)
SB [auth CU]	PF00338	e4ujcCU1	A: a+b two layers	X: Alpha-beta plaits	H: Ribosomal protein S10 (From Topology)	T: Ribosomal protein S10	F: PF00338	ECOD (1.6)
TB [auth CV]	PF01249	e4ujcCV1	A: a+b two layers	X: 40S ribosomal protein rpS21 (S21e) (From Topology)	H: 40S ribosomal protein rpS21 (S21e) (From Topology)	T: 40S ribosomal protein rpS21 (S21e)	F: PF01249	ECOD (1.6)
UB [auth CW]	PF00410	e4ujcCW2	A: a+b two layers	X: R3H domain-like	H: Ribosomal protein S8, N-terminal domain (From Topology)	T: Ribosomal protein S8, N-terminal domain	F: PF00410	ECOD (1.6)
UB [auth CW]	PF00410	e4ujcCW1	A: a+b two layers	X: Ribosomal protein S8, C-terminal domain (From Topology)	H: Ribosomal protein S8, C-terminal domain (From Topology)	T: Ribosomal protein S8, C-terminal domain	F: PF00410	ECOD (1.6)
VB [auth CX]	PF00164	e4ujcCX1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF00164	ECOD (1.6)
WB [auth CY]	PF01282	e4ujcCY1	A: a+b two layers	X: Alpha-beta plaits	H: Ribosomal proteins S24e, L23 and L15e (From Topology)	T: Ribosomal proteins S24e, L23 and L15e	F: PF01282	ECOD (1.6)
XB [auth CZ]	PF03297	e4ujcCZ1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: PF03297	ECOD (1.6)
YB [auth Ca]	PF01283	e4ujcCa1	A: few secondary structure elements	X: Glucocorticoid receptor-like	H: LIM domain-like	T: LIM domain-like	F: PF01283	ECOD (1.6)
ZB [auth Cb]	PF01667	e4ujcCb1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF01667	ECOD (1.6)
AC [auth Cc]	PF01200	e4ujcCc1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF01200	ECOD (1.6)
BC [auth Cd]	PF00253	e4ujcCd1	A: few secondary structure elements	X: Glucocorticoid receptor-like	H: LIM domain-like	T: LIM domain-like	F: PF00253	ECOD (1.6)
DC [auth Cf]	PF01599	e4ujcCf1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF01599	ECOD (1.6)
EC [auth Cg]	PF00400	e4ujcCg1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: PF00400	ECOD (1.6)
CA [auth BX]	PF00276,PF03939	e4ujcBX1	A: a+b two layers	X: Alpha-beta plaits	H: Ribosomal proteins S24e, L23 and L15e (From Topology)	T: Ribosomal proteins S24e, L23 and L15e	F: PF00276,PF03939	ECOD (1.6)
BB [auth CD]	PF00189	e4ujcCD1	A: a+b two layers	X: T-fold	H: Ribosomal protein S3-C (From Topology)	T: Ribosomal protein S3-C	F: PF00189	ECOD (1.6)
BB [auth CD]	PF07650	e4ujcCD2	A: a+b two layers	X: Alpha-lytic protease prodomain-like	H: KH-domains	T: Prokaryotic type KH domain (KH-domain type II)	F: PF07650	ECOD (1.6)
GB [auth CI]	PF01201	e4ujcCI1	A: beta barrels	X: Ribosomal protein L14-like	H: Ribosomal protein L14-related (From Topology)	T: Ribosomal protein L14-related	F: PF01201	ECOD (1.6)
IB [auth CK]	PF03501	e4ujcCK1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: PF03501	ECOD (1.6)
CC [auth Ce]	PF04758	e4ujcCe1	A: extended segments	X: 40S ribosomal protein S30 (S30e) (From Topology)	H: 40S ribosomal protein S30 (S30e) (From Topology)	T: 40S ribosomal protein S30 (S30e)	F: PF04758	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B [auth AB]	PF00009	Elongation factor Tu GTP binding domain (GTP_EFTU)	Elongation factor Tu GTP binding domain	This domain contains a P-loop motif, also found in several other families such as Pfam:PF00071, Pfam:PF00025 and Pfam:PF00063. Elongation factor Tu consists of three structural domains, this plus two C-terminal beta barrel domains.	Domain
B [auth AB]	PF11987	Translation-initiation factor 2 (IF-2)	Translation-initiation factor 2	IF-2 is a translation initiator in each of the three main phylogenetic domains (Eukaryotes [1], Bacteria [2] and Archaea [3]). IF2 interacts with formylmethionine-tRNA, GTP, IF1, IF3 and both ribosomal subunits [2]. Through these interactions, IF2 pr ...	IF-2 is a translation initiator in each of the three main phylogenetic domains (Eukaryotes [1], Bacteria [2] and Archaea [3]). IF2 interacts with formylmethionine-tRNA, GTP, IF1, IF3 and both ribosomal subunits [2]. Through these interactions, IF2 promotes the binding of the initiator tRNA to the A site in the smaller ribosomal subunit and catalyses the hydrolysis of GTP following initiation-complex formation [2].	Domain
B [auth AB]	PF14578	Elongation factor Tu domain 4 (GTP_EFTU_D4)	Elongation factor Tu domain 4	Elongation factor Tu consists of several structural domains, and this is usually the fourth.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth AA]	TRNA	-	-	-
B [auth AB]	EIF5B	translation regulator activity binding organic cyclic compound binding translation regulator activity, nucleic acid binding nucleic acid binding translation initiation factor activity translation factor activity, RNA binding guanyl nucleotide binding GTP binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding translation regulator activity binding organic cyclic compound binding translation regulator activity, nucleic acid binding nucleic acid binding translation initiation factor activity translation factor activity, RNA binding guanyl nucleotide binding GTP binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding pyrophosphatase activity GTPase activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity	-	-
C [auth AC]	HCV-IRES	-	-	-
D [auth A2]	28S RIBOSOMAL RNA	-	-	-
E [auth A3]	5.8S RIBOSOMAL RNA	-	-	-
F [auth A4]	5S RIBOSOMAL RNA	-	-	-
G [auth BA]	60S RIBOSOMAL PROTEIN L8	-	-	-
H [auth BB]	60S RIBOSOMAL PROTEIN L3	-	-	-
I [auth BC]	60S RIBOSOMAL PROTEIN L4	-	-	-
J [auth BD]	60S RIBOSOMAL PROTEIN L5	-	-	-
K [auth BE]	60S RIBOSOMAL PROTEIN L6	-	-	-
L [auth BF]	60S RIBOSOMAL PROTEIN L7	-	-	-
M [auth BG]	60S RIBOSOMAL PROTEIN L7A	-	-	-
N [auth BH]	60S RIBOSOMAL PROTEIN L9	-	-	-
O [auth BI]	60S RIBOSOMAL PROTEIN L10	-	-	-
P [auth BJ]	60S RIBOSOMAL PROTEIN L11	-	-	-
Q [auth BL]	60S RIBOSOMAL PROTEIN L13	-	-	-
R [auth BM]	60S RIBOSOMAL PROTEIN L14	-	-	-
S [auth BN]	60S RIBOSOMAL PROTEIN L15	-	-	-
T [auth BO]	60S RIBOSOMAL PROTEIN L13A	-	-	-
U [auth BP]	60S RIBOSOMAL PROTEIN L17	-	-	-
V [auth BQ]	60S RIBOSOMAL PROTEIN L18	-	-	-
W [auth BR]	60S RIBOSOMAL PROTEIN L19	-	-	-
X [auth BS]	60S RIBOSOMAL PROTEIN L18A	-	-	-
Y [auth BT]	60S RIBOSOMAL PROTEIN L21	-	-	-
Z [auth BU]	60S RIBOSOMAL PROTEIN L22	-	-	-
AA [auth BV]	60S RIBOSOMAL PROTEIN L23	-	-	-
BA [auth BW]	60S RIBOSOMAL PROTEIN L24	-	-	-
DA [auth BY]	60S RIBOSOMAL PROTEIN L26	-	-	-
EA [auth BZ]	60S RIBOSOMAL PROTEIN L27	-	-	-
FA [auth Ba]	60S RIBOSOMAL PROTEIN L27A	-	-	-
GA [auth Bb]	60S RIBOSOMAL PROTEIN L29	-	-	-
HA [auth Bc]	60S RIBOSOMAL PROTEIN L30	-	-	-
IA [auth Bd]	60S RIBOSOMAL PROTEIN L31	-	-	-
JA [auth Be]	60S RIBOSOMAL PROTEIN L32	-	-	-
KA [auth Bf]	60S RIBOSOMAL PROTEIN L35A	-	-	-
LA [auth Bg]	60S RIBOSOMAL PROTEIN L34	-	-	-
MA [auth Bh]	60S RIBOSOMAL PROTEIN UL29	-	-	-
NA [auth Bi]	60S RIBOSOMAL PROTEIN L36	-	-	-
OA [auth Bj]	60S RIBOSOMAL PROTEIN L37	-	-	-
PA [auth Bk]	60S RIBOSOMAL PROTEIN L38	-	-	-
QA [auth Bl]	60S RIBOSOMAL PROTEIN L39	-	-	-
RA [auth Bm]	UBIQUITIN-60S RIBOSOMAL PROTEIN L40	-	-	-
SA [auth Bn]	60S RIBOSOMAL PROTEIN L41	-	-	-
TA [auth Bo]	60S RIBOSOMAL PROTEIN L36A	-	-	-
UA [auth Bp]	60S RIBOSOMAL PROTEIN L37A	-	-	-
VA [auth Bt]	60S RIBOSOMAL PROTEIN L28	-	-	-
WA [auth Bu]	60S RIBOSOMAL PROTEIN L10A	-	-	-
XA [auth C1]	18S RIBOSOMAL RNA	-	-	-
YA [auth CA]	40S RIBOSOMAL PROTEIN US2	-	-	-
ZA [auth CB]	40S RIBOSOMAL PROTEIN ES1	-	-	-
AB [auth CC]	40S RIBOSOMAL PROTEIN US5	-	-	-
CB [auth CE]	40S RIBOSOMAL PROTEIN ES4	-	-	-
DB [auth CF]	40S RIBOSOMAL PROTEIN US7	-	-	-
EB [auth CG]	40S RIBOSOMAL PROTEIN ES6	-	-	-
FB [auth CH]	40S RIBOSOMAL PROTEIN ES7	-	-	-
HB [auth CJ]	40S RIBOSOMAL PROTEIN US4	-	-	-
JB [auth CL]	40S RIBOSOMAL PROTEIN US17	-	-	-
KB [auth CM]	40S RIBOSOMAL PROTEIN ES12	-	-	-
LB [auth CN]	40S RIBOSOMAL PROTEIN US15	-	-	-
MB [auth CO]	40S RIBOSOMAL PROTEIN US11	-	-	-
NB [auth CP]	40S RIBOSOMAL PROTEIN US19	-	-	-
OB [auth CQ]	40S RIBOSOMAL PROTEIN US9	-	-	-
PB [auth CR]	40S RIBOSOMAL PROTEIN ES17	-	-	-
QB [auth CS]	40S RIBOSOMAL PROTEIN US13	-	-	-
RB [auth CT]	40S RIBOSOMAL PROTEIN ES19	-	-	-
SB [auth CU]	40S RIBOSOMAL PROTEIN US10	-	-	-
TB [auth CV]	40S RIBOSOMAL PROTEIN ES21	-	-	-
UB [auth CW]	40S RIBOSOMAL PROTEIN US8	-	-	-
VB [auth CX]	40S RIBOSOMAL PROTEIN US12	-	-	-
WB [auth CY]	40S RIBOSOMAL PROTEIN ES24	-	-	-
XB [auth CZ]	40S RIBOSOMAL PROTEIN ES25	-	-	-
YB [auth Ca]	40S RIBOSOMAL PROTEIN ES26	-	-	-
ZB [auth Cb]	40S RIBOSOMAL PROTEIN ES27	-	-	-
AC [auth Cc]	40S RIBOSOMAL PROTEIN ES28	-	-	-
BC [auth Cd]	40S RIBOSOMAL PROTEIN US14	-	-	-
DC [auth Cf]	40S RIBOSOMAL PROTEIN ES31	-	-	-
EC [auth Cg]	40S RIBOSOMAL PROTEIN RACK1	-	-	-
CA [auth BX]	60S RIBOSOMAL PROTEIN L23A	-	-	-
BB [auth CD]	40S RIBOSOMAL PROTEIN US3	-	-	-
GB [auth CI]	40S RIBOSOMAL PROTEIN ES8	-	-	-
IB [auth CK]	40S RIBOSOMAL PROTEIN ES10	-	-	-
CC [auth Ce]	40S RIBOSOMAL PROTEIN ES30	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B [auth AB]	IPR029459	Elongation factor Tu-type domain	Domain
B [auth AB]	IPR000795	Translational (tr)-type GTP-binding domain	Domain
B [auth AB]	IPR009000	Translation protein, beta-barrel domain superfamily	Homologous Superfamily
B [auth AB]	IPR005225	Small GTP-binding protein domain	Domain
B [auth AB]	IPR015760	Translation initiation factor IF- 2	Family
B [auth AB]	IPR036925	Translation initiation factor IF-2, domain 3 superfamily	Homologous Superfamily
B [auth AB]	IPR023115	Translation initiation factor IF- 2, domain 3	Domain
B [auth AB]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily