4TW1

Crystal structure of the octameric pore complex of the Staphylococcus aureus Bi-component Toxin LukGH

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4tw1a_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
C	d4tw1c_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
E	d4tw1e_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
G	d4tw1g_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
I	d4tw1i_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
K	d4tw1k_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
M	d4tw1m_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
O	d4tw1o_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
B	d4tw1b_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
D	d4tw1d_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
F	d4tw1f_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
H	d4tw1h_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
J	d4tw1j_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
L	d4tw1l_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
N	d4tw1n_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)
P	d4tw1p_	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	automated matches	automated matches	(Staphylococcus aureus subsp. aureus USA300_TCH1516 ) [TaxId: 451516 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Leukocidin	e4tw1A1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
C	Leukocidin	e4tw1C1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
E	Leukocidin	e4tw1E1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
G	Leukocidin	e4tw1G1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
I	Leukocidin	e4tw1I1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
K	Leukocidin	e4tw1K1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
M	Leukocidin	e4tw1M1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
O	Leukocidin	e4tw1O1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
B	Leukocidin	e4tw1B1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
D	Leukocidin	e4tw1D1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
F	Leukocidin	e4tw1F1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
H	Leukocidin	e4tw1H1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
J	Leukocidin	e4tw1J1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
L	Leukocidin	e4tw1L1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
N	Leukocidin	e4tw1N1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)
P	Leukocidin	e4tw1P1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: Leukocidin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
C	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
E	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
G	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
I	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
K	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
M	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
O	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
B	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
D	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
F	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
H	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
J	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
L	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
N	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)
P	2.70.240.10	Mainly Beta	Distorted Sandwich	Leukocidin-like	Leukocidin/porin MspA	CATH (4.3.0)

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.