4RCW

Crystal structure of human Slitrk1

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APF13855e4rcwA1 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: PF13855ECOD (1.6)
BPF13855e4rcwB1 A: beta duplicates or obligate multimersX: Single-stranded right-handed beta-helixH: Leucine-rich repeats (From Topology)T: Leucine-rich repeatsF: PF13855ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease InhibitorCATH (4.3.0)
B3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease InhibitorCATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
SLIT and NTRK-like protein 1-

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B
IPR043326Slitrk familyFamily
A, B
IPR001611Leucine-rich repeatRepeat
A, B
IPR003591Leucine-rich repeat, typical subtypeRepeat
A, B
IPR032675Leucine-rich repeat domain superfamilyHomologous Superfamily
A, B
IPR000483Cysteine-rich flanking region, C-terminalDomain

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, B
Pharos:  Q96PX8