4RBN

The crystal structure of Nitrosomonas europaea sucrose synthase: Insights into the evolutionary origin of sucrose metabolism in prokaryotes

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00862	e4rbnA3	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
A	PF00862	e4rbnA4	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
A	PF00534	e4rbnA2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
A	PF00862	e4rbnA1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)
B [auth C]	PF00862	e4rbnC3	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
B [auth C]	PF00862	e4rbnC4	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
B [auth C]	PF00534	e4rbnC2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
B [auth C]	PF00862	e4rbnC1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)
C [auth B]	PF00862	e4rbnB3	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
C [auth B]	PF00862	e4rbnB4	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
C [auth B]	PF00534	e4rbnB2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
C [auth B]	PF00862	e4rbnB1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)
D	PF00862	e4rbnD3	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
D	PF00862	e4rbnD4	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
D	PF00534	e4rbnD2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
D	PF00862	e4rbnD1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
A	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
A	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
B [auth C]	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
B [auth C]	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
B [auth C]	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
C [auth B]	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
C [auth B]	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
C [auth B]	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
D	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
D	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
D	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B [auth C], C [auth B], D	PF00534	Glycosyl transferases group 1 (Glycos_transf_1)	Glycosyl transferases group 1	-	Family
A, B [auth C], C [auth B], D	PF00862	Sucrose synthase (Sucrose_synth)	Sucrose synthase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B [auth C], C [auth B], D	Sucrose synthase:Glycosyl transferases group 1	UDP-glycosyltransferase activity glycosyltransferase activity transferase activity glucosyltransferase activity hexosyltransferase activity catalytic activity sucrose synthase activity UDP-glucosyltransferase activity	sucrose metabolic process carbohydrate metabolic process organic substance metabolic process oligosaccharide metabolic process primary metabolic process metabolic process disaccharide metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B [auth C], C [auth B], D	IPR012820	Sucrose synthase, plant/cyanobacteria	Family
A, B [auth C], C [auth B], D	IPR000368	Sucrose synthase	Domain
A, B [auth C], C [auth B], D	IPR001296	Glycosyl transferase, family 1	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.