Annotations: 4R7Y

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4r7ya1	All beta proteins	OB-fold	Nucleic acid-binding proteins	DNA replication initiator (cdc21/cdc54) N-terminal domain	automated matches	(Saccharolobus solfataricus P2 ) [TaxId: 273057 ], (Pyrococcus furiosus DSM 3638 ) [TaxId: 186497 ], (Pyrococcus furiosus DSM 3638 ) [TaxId: 186497 ],	SCOPe (2.08)
A	d4r7ya2	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	automated matches	automated matches	(Saccharolobus solfataricus P2 ) [TaxId: 273057 ], (Pyrococcus furiosus DSM 3638 ) [TaxId: 186497 ], (Pyrococcus furiosus DSM 3638 ) [TaxId: 186497 ],	SCOPe (2.08)
B	d4r7yb1	All beta proteins	OB-fold	Nucleic acid-binding proteins	DNA replication initiator (cdc21/cdc54) N-terminal domain	automated matches	(Saccharolobus solfataricus P2 ) [TaxId: 273057 ], (Pyrococcus furiosus DSM 3638 ) [TaxId: 186497 ], (Pyrococcus furiosus DSM 3638 ) [TaxId: 186497 ],	SCOPe (2.08)
B	d4r7yb2	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	automated matches	automated matches	(Saccharolobus solfataricus P2 ) [TaxId: 273057 ], (Pyrococcus furiosus DSM 3638 ) [TaxId: 186497 ], (Pyrococcus furiosus DSM 3638 ) [TaxId: 186497 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF17207	e4r7yA4	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17207	ECOD (1.6)
A	PF17855	e4r7yA5	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: PF17855	ECOD (1.6)
A	PF14551	e4r7yA3	A: a+b complex topology	X: N-terminal subdomain in DNA replication initiator (cdc21/cdc54) (From Topology)	H: N-terminal subdomain in DNA replication initiator (cdc21/cdc54) (From Topology)	T: N-terminal subdomain in DNA replication initiator (cdc21/cdc54)	F: PF14551	ECOD (1.6)
A	PF00493	e4r7yA1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00493	ECOD (1.6)
A	F_UNCLASSIFIED	e4r7yA2	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF17207	e4r7yB5	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17207	ECOD (1.6)
B	PF17855	e4r7yB3	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: PF17855	ECOD (1.6)
B	PF14551	e4r7yB2	A: a+b complex topology	X: N-terminal subdomain in DNA replication initiator (cdc21/cdc54) (From Topology)	H: N-terminal subdomain in DNA replication initiator (cdc21/cdc54) (From Topology)	T: N-terminal subdomain in DNA replication initiator (cdc21/cdc54)	F: PF14551	ECOD (1.6)
B	PF00493	e4r7yB4	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00493	ECOD (1.6)
B	F_UNCLASSIFIED	e4r7yB1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: F_UNCLASSIFIED	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.1640.10	Alpha Beta	2-Layer Sandwich	mini-chromosome maintenance (MCM) complex, chain A, domain 1	mini-chromosome maintenance (MCM) complex, chain A, domain 1	CATH (4.3.0)
A	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
A	2.20.28.10	Mainly Beta	Single Sheet	Rubrerythrin, domain 2		CATH (4.3.0)
A	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
B	3.30.1640.10	Alpha Beta	2-Layer Sandwich	mini-chromosome maintenance (MCM) complex, chain A, domain 1	mini-chromosome maintenance (MCM) complex, chain A, domain 1	CATH (4.3.0)
B	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
B	2.20.28.10	Mainly Beta	Single Sheet	Rubrerythrin, domain 2		CATH (4.3.0)
B	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF14551	MCM N-terminal domain (MCM_N)	MCM N-terminal domain	This family contains the N-terminal domain of MCM proteins.	Domain
A, B	PF17855	MCM AAA-lid domain (MCM_lid)	MCM AAA-lid domain	This entry represents the AAA-lid domain found in MCM proteins.	Domain
A, B	PF17207	MCM OB domain (MCM_OB)	MCM OB domain	This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif [2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Minichromosome maintenance protein MCM, Cell division control protein 21	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding DNA binding nucleic acid binding endonuclease activity nuclease activity hydrolase activity, acting on ester bonds hydrolase activity catalytic activity cation binding metal ion binding catalytic activity, acting on a nucleic acid helicase activity ATP-dependent activity pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity, acting on acid anhydrides identical protein binding protein binding single-stranded DNA binding	intein-mediated protein splicing organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process biosynthetic process proteolysis organic substance biosynthetic process protein processing metabolic process intein-mediated protein splicing organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process biosynthetic process proteolysis organic substance biosynthetic process protein processing metabolic process cellular process protein metabolic process macromolecule metabolic process protein splicing cell division cellular component organization DNA duplex unwinding organelle organization DNA geometric change chromosome organization DNA conformation change cellular component organization or biogenesis nucleobase-containing compound metabolic process organic cyclic compound metabolic process DNA replication DNA metabolic process nucleic acid metabolic process	protein-containing complex MCM complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR036844	Hint domain superfamily	Homologous Superfamily
A, B	IPR027925	MCM, N-terminal domain	Domain
A, B	IPR031327	Mini-chromosome maintenance protein	Family
A, B	IPR006142	Intein	Domain
A, B	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
A, B	IPR004042	Intein DOD homing endonuclease	Domain
A, B	IPR006141	Intein N-terminal splicing region	PTM
A, B	IPR033762	MCM OB domain	Domain
A, B	IPR003587	Hint domain N-terminal	Domain
A, B	IPR001208	MCM domain	Domain
A, B	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
A, B	IPR041562	MCM, AAA-lid domain	Domain
A, B	IPR030934	Intein C-terminal splicing region	Domain
A, B	IPR003586	Hint domain C-terminal	Domain
A, B	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
A, B	IPR048908	Minichromosome maintenance protein MCM, C-terminal domain	Domain
A, B	IPR027925	MCM, N-terminal domain	Domain
A, B	IPR031327	Mini-chromosome maintenance protein	Family
A, B	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
A, B	IPR033762	MCM OB domain	Domain
A, B	IPR003593	AAA+ ATPase domain	Domain
A, B	IPR001208	MCM domain	Domain
A, B	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
A, B	IPR041562	MCM, AAA-lid domain	Domain
A, B	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily