4QLE
Crystal structure of I14A DHFR mutant complexed with folate and NADP+
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
| Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| B | d4qleb_ | Alpha and beta proteins (a/b) | Dihydrofolate reductase-like | Dihydrofolate reductase-like | Dihydrofolate reductases | Dihydrofolate reductase, prokaryotic type | (Escherichia coli str. K-12 substr. MC4100 ) [TaxId: 1403831 ], | SCOPe (2.08) |
| A | d4qlea_ | Alpha and beta proteins (a/b) | Dihydrofolate reductase-like | Dihydrofolate reductase-like | Dihydrofolate reductases | Dihydrofolate reductase, prokaryotic type | (Escherichia coli str. K-12 substr. MC4100 ) [TaxId: 1403831 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| B | DHFR_1 | e4qleB1 | A: a/b three-layered sandwiches | X: Dihydrofolate reductases (From Topology) | H: Dihydrofolate reductases (From Topology) | T: Dihydrofolate reductases | F: DHFR_1 | ECOD (1.6) |
| A | DHFR_1 | e4qleA1 | A: a/b three-layered sandwiches | X: Dihydrofolate reductases (From Topology) | H: Dihydrofolate reductases (From Topology) | T: Dihydrofolate reductases | F: DHFR_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
| Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
|---|---|---|---|---|---|---|
| B | 3.40.430.10 | Alpha Beta | 3-Layer(aba) Sandwich | Dihydrofolate Reductase, subunit A | Dihydrofolate Reductase, subunit A | CATH (4.3.0) |
| A | 3.40.430.10 | Alpha Beta | 3-Layer(aba) Sandwich | Dihydrofolate Reductase, subunit A | Dihydrofolate Reductase, subunit A | CATH (4.3.0) |
