4QI7

Cellobiose dehydrogenase from Neurospora crassa, NcCDH

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF16010	e4qi7A2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF16010	ECOD (1.6)
A	PF00732,PF05199	e4qi7A1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: PF00732,PF05199	ECOD (1.6)
A	PF00734	e4qi7A3	A: few secondary structure elements	X: omega toxin-like	H: omega toxin-related	T: omega toxin-related	F: PF00734	ECOD (1.6)
B	PF16010	e4qi7B3	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF16010	ECOD (1.6)
B	PF00732,PF05199	e4qi7B2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: PF00732,PF05199	ECOD (1.6)
B	PF00734	e4qi7B1	A: few secondary structure elements	X: omega toxin-like	H: omega toxin-related	T: omega toxin-related	F: PF00734	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00732	GMC oxidoreductase (GMC_oxred_N)	GMC oxidoreductase	This family of proteins bind FAD as a cofactor.	Domain
A, B	PF00734	Fungal cellulose binding domain (CBM_1)	Fungal cellulose binding domain	-	Domain
A, B	PF05199	GMC oxidoreductase (GMC_oxred_C)	GMC oxidoreductase	This domain found associated with Pfam:PF00732.	Domain
A, B	PF16010	Cytochrome domain of cellobiose dehydrogenase (CDH-cyt)	Cytochrome domain of cellobiose dehydrogenase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Cellobiose dehydrogenase	binding polysaccharide binding cellulose binding carbohydrate binding oxidoreductase activity oxidoreductase activity, acting on CH-OH group of donors catalytic activity cellobiose dehydrogenase (acceptor) activity cation binding ion binding metal ion binding small molecule binding flavin adenine dinucleotide binding nucleoside phosphate binding binding polysaccharide binding cellulose binding carbohydrate binding oxidoreductase activity oxidoreductase activity, acting on CH-OH group of donors catalytic activity cellobiose dehydrogenase (acceptor) activity cation binding ion binding metal ion binding small molecule binding flavin adenine dinucleotide binding nucleoside phosphate binding organic cyclic compound binding anion binding nucleotide binding heterocyclic compound binding	carbohydrate metabolic process organic substance metabolic process primary metabolic process metabolic process	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR015920	Cellobiose dehydrogenase, cytochrome domain	Domain
A, B	IPR000172	Glucose-methanol-choline oxidoreductase, N-terminal	Domain
A, B	IPR000254	Cellulose-binding domain, fungal	Domain
A, B	IPR007867	Glucose-methanol-choline oxidoreductase, C-terminal	Domain
A, B	IPR036188	FAD/NAD(P)-binding domain superfamily	Homologous Superfamily
A, B	IPR035971	Cellulose-binding domain superfamily	Homologous Superfamily

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, B	PCA	Parent Component: GLN RESID: AA0031 PSI-MOD : 2-pyrrolidone-5-carboxylic acid (Gln) MOD:00040 , 2-pyrrolidone-5-carboxylic acid (Glu) MOD:00420

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.