Annotations: 4QH7

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	DLC-like	8040999	3000821	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	DLC-like	8040999	3000821	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	DLC-like	8040999	3000821	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	DLC-like	8040999	3000821	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Dynein_light	e4qh7A1	A: a+b two layers	X: DLC (From Topology)	H: DLC (From Topology)	T: DLC	F: Dynein_light	ECOD (1.6)
B	Dynein_light	e4qh7B1	A: a+b two layers	X: DLC (From Topology)	H: DLC (From Topology)	T: DLC	F: Dynein_light	ECOD (1.6)
E	Dynein_light	e4qh7E1	A: a+b two layers	X: DLC (From Topology)	H: DLC (From Topology)	T: DLC	F: Dynein_light	ECOD (1.6)
F	Dynein_light	e4qh7F1	A: a+b two layers	X: DLC (From Topology)	H: DLC (From Topology)	T: DLC	F: Dynein_light	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.740.10	Alpha Beta	2-Layer Sandwich	Protein Inhibitor Of Neuronal Nitric Oxide Synthase	Protein Inhibitor Of Neuronal Nitric Oxide Synthase	CATH (4.3.0)
B	3.30.740.10	Alpha Beta	2-Layer Sandwich	Protein Inhibitor Of Neuronal Nitric Oxide Synthase	Protein Inhibitor Of Neuronal Nitric Oxide Synthase	CATH (4.3.0)
E	3.30.740.10	Alpha Beta	2-Layer Sandwich	Protein Inhibitor Of Neuronal Nitric Oxide Synthase	Protein Inhibitor Of Neuronal Nitric Oxide Synthase	CATH (4.3.0)
F	3.30.740.10	Alpha Beta	2-Layer Sandwich	Protein Inhibitor Of Neuronal Nitric Oxide Synthase	Protein Inhibitor Of Neuronal Nitric Oxide Synthase	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, E, F	PF01221	Dynein light chain type 1 (Dynein_light)	Dynein light chain type 1	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, E, F	Dynein light chain 1, cytoplasmic	identical protein binding protein binding binding protein homodimerization activity protein dimerization activity dynein light intermediate chain binding dynein intermediate chain binding disordered domain specific binding protein domain specific binding	developmental process spermatogenesis sexual reproduction reproductive process multicellular organismal reproductive process developmental process involved in reproduction male gamete generation gamete generation cellular developmental process oogenesis cell development cellular process involved in reproduction in multicellular organism female gamete generation cell differentiation developmental process spermatogenesis sexual reproduction reproductive process multicellular organismal reproductive process developmental process involved in reproduction male gamete generation gamete generation cellular developmental process oogenesis cell development cellular process involved in reproduction in multicellular organism female gamete generation cell differentiation anatomical structure development germ cell development cellular process multicellular organismal process regulation of neuron remodeling regulation of cellular process regulation of developmental process positive regulation of biological process regulation of cell differentiation positive regulation of cell maturation regulation of neuron maturation positive regulation of neuron remodeling regulation of cell development positive regulation of developmental process neurogenesis multicellular organism development neuron differentiation positive regulation of cell differentiation neuron remodeling cell maturation regulation of cell maturation positive regulation of cellular process system development regulation of biological process positive regulation of neuron maturation biological regulation positive regulation of cell development developmental maturation nervous system development generation of neurons anatomical structure maturation neuron development neuron maturation regulation of neuron differentiation spermatid development spermatid differentiation cellularization sperm individualization anatomical structure morphogenesis anatomical structure formation involved in morphogenesis imaginal disc development animal organ development wing disc development cellular catabolic process catabolic process cellular metabolic process autophagy metabolic process process utilizing autophagic mechanism imaginal disc morphogenesis appendage development post-embryonic appendage morphogenesis imaginal disc-derived wing morphogenesis instar larval or pupal development metamorphosis imaginal disc-derived appendage morphogenesis wing disc morphogenesis appendage morphogenesis imaginal disc-derived appendage development instar larval or pupal morphogenesis post-embryonic animal morphogenesis post-embryonic development animal organ morphogenesis chaeta morphogenesis chaeta development sensory organ development establishment of organelle localization cellular localization microtubule cytoskeleton organization spindle localization establishment or maintenance of cell polarity mitotic cell cycle cellular component organization localization establishment of mitotic spindle localization establishment of spindle localization establishment of spindle orientation organelle localization establishment of localization in cell cell cycle cellular component organization or biogenesis microtubule cytoskeleton organization involved in mitosis cell cycle process establishment of localization establishment of cell polarity organelle organization mitotic cell cycle process establishment of mitotic spindle orientation microtubule-based process cytoskeleton organization spermatid nucleus elongation nucleus organization spermatid nucleus differentiation microtubule anchoring at microtubule organizing center microtubule anchoring at centrosome microtubule anchoring actin cytoskeleton organization actin filament organization cellular component biogenesis cellular component assembly actin filament bundle organization actin filament bundle assembly actin filament-based process supramolecular fiber organization	intracellular organelle microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle centriole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle cytoplasm protein-containing complex cytoplasmic dynein complex catalytic complex intracellular organelle microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle centriole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle cytoplasm protein-containing complex cytoplasmic dynein complex catalytic complex dynein complex microtubule associated complex polymeric cytoskeletal fiber supramolecular fiber microtubule supramolecular polymer supramolecular complex
C, D, G, H	Anastral spindle 2	-	developmental process neuroblast proliferation multicellular organismal process cell population proliferation cellular developmental process neuroblast division nervous system development asymmetric cell division generation of neurons neurogenesis multicellular organism development asymmetric neuroblast division cell differentiation anatomical structure development developmental process neuroblast proliferation multicellular organismal process cell population proliferation cellular developmental process neuroblast division nervous system development asymmetric cell division generation of neurons neurogenesis multicellular organism development asymmetric neuroblast division cell differentiation anatomical structure development cellular process cell division neural precursor cell proliferation cell fate commitment system development microtubule organizing center organization microtubule cytoskeleton organization centriole-centriole cohesion cellular component organization organelle organization centrosome cycle microtubule-based process cell cycle cellular component organization or biogenesis cytoskeleton organization cell cycle process establishment of organelle localization cellular localization spindle localization establishment or maintenance of cell polarity mitotic cell cycle localization establishment of mitotic spindle localization establishment of spindle localization establishment of spindle orientation organelle localization establishment of localization in cell microtubule cytoskeleton organization involved in mitosis establishment of localization establishment of cell polarity mitotic cell cycle process establishment of mitotic spindle orientation centriole assembly organelle assembly non-membrane-bounded organelle assembly cellular component biogenesis cellular component assembly microtubule anchoring at microtubule organizing center microtubule anchoring at centrosome microtubule anchoring centrosome duplication centriole replication plasma membrane bounded cell projection organization cell projection organization ciliary basal body organization cilium organization	intracellular organelle microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle centriole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle membrane-bounded organelle cilium plasma membrane bounded cell projection ciliary basal body intracellular organelle microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle centriole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle membrane-bounded organelle cilium plasma membrane bounded cell projection ciliary basal body cell projection centrosome

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, E, F	IPR037177	Dynein light chain superfamily	Homologous Superfamily
A, B, E, F	IPR019763	Dynein light chain, type 1/2, conserved site	Conserved Site
A, B, E, F	IPR001372	Dynein light chain, type 1/2	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.