4QAB

X-RAY STRUCTURE of ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 4-(MORPHOLIN-4-YL)-6-[4-(TRIFLUOROMETHYL)PHENYL]PYRIMIDIN-2-AMINE

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4qaba1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
A	d4qaba2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
B	d4qabb1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
B	d4qabb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
C	d4qabc1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
C	d4qabc2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
D	d4qabd1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
D	d4qabd2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
E	d4qabe1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
E	d4qabe2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
F	d4qabf1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
F	d4qabf2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
G	d4qabg1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
G	d4qabg2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
H	d4qabh1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
H	d4qabh2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
I	d4qabi1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
I	d4qabi2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
J	d4qabj1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
J	d4qabj2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02931	e4qabA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: PF02931	ECOD (1.6)
B	PF02931	e4qabB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: PF02931	ECOD (1.6)
C	PF02931	e4qabC1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: PF02931	ECOD (1.6)
D	PF02931	e4qabD1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: PF02931	ECOD (1.6)
E	PF02931	e4qabE1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: PF02931	ECOD (1.6)
F	PF02931	e4qabF1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: PF02931	ECOD (1.6)
G	PF02931	e4qabG1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: PF02931	ECOD (1.6)
H	PF02931	e4qabH1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: PF02931	ECOD (1.6)
I	PF02931	e4qabI1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: PF02931	ECOD (1.6)
J	PF02931	e4qabJ1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: PF02931	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
B	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
C	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
D	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
E	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
F	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
G	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
H	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
I	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
J	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	PF02931	Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD)	Neurotransmitter-gated ion-channel ligand binding domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	Acetylcholine-binding protein	ligand-gated channel activity ligand-gated monoatomic ion channel activity extracellular ligand-gated monoatomic ion channel activity passive transmembrane transporter activity gated channel activity monoatomic ion channel activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity molecular transducer activity transmembrane signaling receptor activity signaling receptor activity	-	synaptic cleft extracellular region cellular anatomical entity membrane synapse cell junction

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	IPR007110	Immunoglobulin-like domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	IPR006201	Neurotransmitter-gated ion-channel	Family

Prepare Data

Validate Data

Deposit Data

Help and Resources

4QAB

X-RAY STRUCTURE of ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 4-(MORPHOLIN-4-YL)-6-[4-(TRIFLUOROMETHYL)PHENYL]PYRIMIDIN-2-AMINE

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Domain Annotation: ECOD Classification ECOD Database Homepage

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage