4OWF
Crystal structure of the NEMO CoZi in complex with HOIP NZF1 domain
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2 Family | NEMO CC2-LZ-like | 8045694 | 4004622 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | NEMO CC2-LZ-like | 8090863 | 3002465 | SCOP2 (2022-06-29) |
B | SCOP2B Superfamily | NEMO CC2-LZ-like | 8090863 | 3002465 | SCOP2B (2022-06-29) |
C [auth G] | SCOP2 Family | Ran binding protein zinc finger-like | 8081676 | 4000343 | SCOP2 (2022-06-29) |
C [auth G] | SCOP2 Superfamily | Ran binding protein zinc finger-like | 8081677 | 3000133 | SCOP2 (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
C [auth G] | PF00641 | e4owfG1 | A: few secondary structure elements | X: Rubredoxin-like | H: Rubredoxin-related | T: Rubredoxin-related | F: PF00641 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 1.20.5.990 | Mainly Alpha | Up-down Bundle | Single alpha-helices involved in coiled-coils or other helix-helix interfaces | Nemo cc2-lz domain - 1d5 darpin complex | CATH (4.3.0) |
B | 1.20.5.990 | Mainly Alpha | Up-down Bundle | Single alpha-helices involved in coiled-coils or other helix-helix interfaces | Nemo cc2-lz domain - 1d5 darpin complex | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF16516 | Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator (CC2-LZ) | Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator | - | Coiled-coil | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
C [auth G] | Q96EP0 | :