4OJ8

Crystal structure of carbapenem synthase in complex with (3S,5S)-carbapenam

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4oj8a1	All beta proteins	Double-stranded beta-helix	Clavaminate synthase-like	gamma-Butyrobetaine hydroxylase	Carbapenem synthase, CarC	(Pectobacterium carotovorum subsp. carotovorum ) [TaxId: 555 ],	SCOPe (2.08)
A	d4oj8a2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pectobacterium carotovorum subsp. carotovorum ) [TaxId: 555 ],	SCOPe (2.08)
B	d4oj8b1	All beta proteins	Double-stranded beta-helix	Clavaminate synthase-like	gamma-Butyrobetaine hydroxylase	Carbapenem synthase, CarC	(Pectobacterium carotovorum subsp. carotovorum ) [TaxId: 555 ],	SCOPe (2.08)
B	d4oj8b2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pectobacterium carotovorum subsp. carotovorum ) [TaxId: 555 ],	SCOPe (2.08)
C	d4oj8c1	All beta proteins	Double-stranded beta-helix	Clavaminate synthase-like	gamma-Butyrobetaine hydroxylase	Carbapenem synthase, CarC	(Pectobacterium carotovorum subsp. carotovorum ) [TaxId: 555 ],	SCOPe (2.08)
C	d4oj8c2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pectobacterium carotovorum subsp. carotovorum ) [TaxId: 555 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Clavaminate synthase-like	8033697	3001848	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Clavaminate synthase-like	8033697	3001848	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Clavaminate synthase-like	8033697	3001848	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	TauD	e4oj8A1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: TauD	ECOD (1.6)
B	TauD	e4oj8B1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: TauD	ECOD (1.6)
C	TauD	e4oj8C1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: TauD	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.60.130.10	Alpha Beta	4-Layer Sandwich	Double-stranded beta-helix	Clavaminate synthase-like	CATH (4.3.0)
B	3.60.130.10	Alpha Beta	4-Layer Sandwich	Double-stranded beta-helix	Clavaminate synthase-like	CATH (4.3.0)
C	3.60.130.10	Alpha Beta	4-Layer Sandwich	Double-stranded beta-helix	Clavaminate synthase-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF02668	Taurine catabolism dioxygenase TauD, TfdA family (TauD)	Taurine catabolism dioxygenase TauD, TfdA family	This family consists of taurine catabolism dioxygenases of the TauD, TfdA family. TauD from E. coli Swiss:P37610 is a alpha-ketoglutarate-dependent taurine dioxygenase [1]. This enzyme catalyses the oxygenolytic release of sulfite from taurine [1]. ...	This family consists of taurine catabolism dioxygenases of the TauD, TfdA family. TauD from E. coli Swiss:P37610 is a alpha-ketoglutarate-dependent taurine dioxygenase [1]. This enzyme catalyses the oxygenolytic release of sulfite from taurine [1]. TfdA from Burkholderia sp. Swiss:Q45423 is a 2,4-dichlorophenoxyacetic acid/alpha-ketoglutarate dioxygenase [2]. TfdA from Alcaligenes eutrophus JMP134 Swiss:P10088 is a 2,4-dichlorophenoxyacetate monooxygenase [3]. Also included are gamma-Butyrobetaine hydroxylase enzymes EC:1.14.11.1 [4].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	(5R)-carbapenem-3-carboxylate synthase	oxidoreductase activity catalytic activity dioxygenase activity cation binding ion binding binding metal ion binding small molecule binding	antibiotic metabolic process biosynthetic process metabolic process antibiotic biosynthetic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR003819	TauD/TfdA-like domain	Domain
A, B, C	IPR042098	Taurine dioxygenase TauD-like superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.