4OFI

Crystal Structure of Duf (Kirre) D1

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C	PF07686	e4ofiC1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF07686	ECOD (1.6)
A	PF07686	e4ofiA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF07686	ECOD (1.6)
B	PF07686	e4ofiB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF07686	ECOD (1.6)
D	PF07686	e4ofiD1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF07686	ECOD (1.6)
E	PF07686	e4ofiE1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF07686	ECOD (1.6)
F	PF07686	e4ofiF1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF07686	ECOD (1.6)
G	PF07686	e4ofiG1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF07686	ECOD (1.6)
H	PF07686	e4ofiH1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF07686	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
A	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
B	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
D	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
E	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
F	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
G	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
H	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF07686	Immunoglobulin V-set domain (V-set)	Immunoglobulin V-set domain	This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Kin of irre, isoform A	cell adhesion molecule binding protein binding binding	cell adhesion cell-cell adhesion cellular process cell-cell adhesion via plasma-membrane adhesion molecules developmental process regulation of muscle tissue development regulation of biological process regulation of developmental process biological regulation animal organ development regulation of striated muscle tissue development tissue development striated muscle tissue development muscle structure development cell adhesion cell-cell adhesion cellular process cell-cell adhesion via plasma-membrane adhesion molecules developmental process regulation of muscle tissue development regulation of biological process regulation of developmental process biological regulation animal organ development regulation of striated muscle tissue development tissue development striated muscle tissue development muscle structure development regulation of muscle organ development anatomical structure development muscle tissue development muscle organ development renal filtration cell differentiation multicellular organismal process cellular developmental process garland nephrocyte differentiation embryo development renal system development embryonic development via the syncytial blastoderm multicellular organism development embryo development ending in birth or egg hatching cell differentiation nephrocyte differentiation system development heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules sensory organ development eye development visual system development eye morphogenesis anatomical structure morphogenesis compound eye development compound eye morphogenesis sensory organ morphogenesis animal organ morphogenesis sensory system development chaeta morphogenesis chaeta development cellular component organization cellular component biogenesis cell junction organization cellular component assembly cell junction assembly filtration diaphragm assembly cellular component organization or biogenesis cell-cell junction assembly cell-cell junction organization renal system process system process nephrocyte filtration renal filtration photoreceptor cell differentiation neurogenesis neuron differentiation eye photoreceptor cell differentiation nervous system development generation of neurons compound eye photoreceptor cell differentiation myoblast fusion cell-cell fusion muscle cell differentiation myotube differentiation syncytium formation by plasma membrane fusion anatomical structure formation involved in morphogenesis syncytium formation striated muscle cell differentiation homophilic cell adhesion via plasma membrane adhesion molecules adherens junction organization adherens junction assembly nephrocyte diaphragm assembly visceral muscle development larval development post-embryonic development larval visceral muscle development regulation of syncytium formation by plasma membrane fusion regulation of cellular component organization regulation of cellular process regulation of myoblast fusion	cell periphery apical part of cell membrane plasma membrane plasma membrane region cellular anatomical entity apical plasma membrane nephrocyte diaphragm cell-cell junction anchoring junction cell junction filtration diaphragm protein-containing complex protein complex involved in cell adhesion

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR036179	Immunoglobulin-like domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR003599	Immunoglobulin subtype	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR003598	Immunoglobulin subtype 2	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR013106	Immunoglobulin V-set domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR013162	CD80-like, immunoglobulin C2-set	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR007110	Immunoglobulin-like domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.