4NAR

Crystal Structure of the Q9WYS3 protein from Thermotoga maritima. Northeast Structural Genomics Consortium Target VR152

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Lactate racemase-like	8045708	4004630	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Lactate racemase N-terminal domain-like	8091611	3002525	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Lactate racemase C-terminal domain-like	8091612	3002526	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF09861	e4narA1	A: a/b three-layered sandwiches	X: Lactate racemase N-terminal domain (From Topology)	H: Lactate racemase N-terminal domain (From Topology)	T: Lactate racemase N-terminal domain	F: PF09861	ECOD (1.6)
A	F_UNCLASSIFIED	e4narA2	A: a/b three-layered sandwiches	X: Lactate racemase C-terminal domain (From Topology)	H: Lactate racemase C-terminal domain (From Topology)	T: Lactate racemase C-terminal domain	F: F_UNCLASSIFIED	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.11440	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	LarA, N-terminal domain	CATH (4.3.0)
A	3.90.226.30	Alpha Beta	Alpha-Beta Complex	2-enoyl-CoA Hydratase	Chain A, domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF09861	Lactate racemase N-terminal domain (Lar_N)	Lactate racemase N-terminal domain	This is the N-terminal domain found in Lactate racemase enzymes EC:5.1.2.1. LarA is a nickel-dependent lactate racemase from the larA-E operon of Lactobacillus plantarum, whereas LarB, LarC and LarE are accessory proteins required for the incorporati ...	This is the N-terminal domain found in Lactate racemase enzymes EC:5.1.2.1. LarA is a nickel-dependent lactate racemase from the larA-E operon of Lactobacillus plantarum, whereas LarB, LarC and LarE are accessory proteins required for the incorporation of Ni in the lactate racemase apoprotein. LarA contains 18 beta-strands and 16 alpha-helices arranged in a novel fold composed of two domains of similar size. This entry represents the N-terminal domain of LarA and related proteins [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Putative uronate isomerase	racemase and epimerase activity, acting on hydroxy acids and derivatives isomerase activity racemase and epimerase activity lactate racemase activity catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR043166	LarA-like, C-terminal domain	Homologous Superfamily
A	IPR048068	LarA-like	Family
A	IPR018657	LarA-like, N-terminal	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.