4LDY

Crystal structure of the DNA binding domain of the G245A mutant of arabidopsis thaliana auxin reponse factor 1

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	B3	e4ldyA1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Type II restriction endonuclease effector domain	F: B3	ECOD (1.6)
A	Auxin_resp_C	e4ldyA3	A: beta barrels	X: SH3	H: Auxin response factor dimerization domain and ancillary domain (From Topology)	T: Auxin response factor dimerization domain and ancillary domain	F: Auxin_resp_C	ECOD (1.6)
A	Auxin_resp_N	e4ldyA2	A: beta barrels	X: SH3	H: Auxin response factor dimerization domain and ancillary domain (From Topology)	T: Auxin response factor dimerization domain and ancillary domain	F: Auxin_resp_N	ECOD (1.6)
B	B3	e4ldyB1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Type II restriction endonuclease effector domain	F: B3	ECOD (1.6)
B	Auxin_resp_C	e4ldyB3	A: beta barrels	X: SH3	H: Auxin response factor dimerization domain and ancillary domain (From Topology)	T: Auxin response factor dimerization domain and ancillary domain	F: Auxin_resp_C	ECOD (1.6)
B	Auxin_resp_N	e4ldyB2	A: beta barrels	X: SH3	H: Auxin response factor dimerization domain and ancillary domain (From Topology)	T: Auxin response factor dimerization domain and ancillary domain	F: Auxin_resp_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.40.330.10	Mainly Beta	Beta Barrel	At1g16640 B3 domain	DNA-binding pseudobarrel domain	CATH (4.3.0)
A	2.30.30.1040	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
B	2.40.330.10	Mainly Beta	Beta Barrel	At1g16640 B3 domain	DNA-binding pseudobarrel domain	CATH (4.3.0)
B	2.30.30.1040	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF06507	Auxin response factor (Auxin_resp)	Auxin response factor	-	Family
A, B	PF02362	B3 DNA binding domain (B3)	B3 DNA binding domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Auxin response factor 1	DNA binding binding organic cyclic compound binding nucleic acid binding transcription regulator activity DNA-binding transcription factor activity sequence-specific DNA binding identical protein binding protein binding	regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process negative regulation of RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription regulation of RNA metabolic process organic substance biosynthetic process negative regulation of nucleobase-containing compound metabolic process regulation of nucleobase-containing compound metabolic process negative regulation of DNA-templated transcription regulation of biological process cellular metabolic process regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process negative regulation of RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription regulation of RNA metabolic process organic substance biosynthetic process negative regulation of nucleobase-containing compound metabolic process regulation of nucleobase-containing compound metabolic process negative regulation of DNA-templated transcription regulation of biological process cellular metabolic process negative regulation of metabolic process primary metabolic process regulation of cellular metabolic process negative regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process negative regulation of macromolecule biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process regulation of DNA-templated transcription regulation of metabolic process negative regulation of RNA metabolic process cellular biosynthetic process RNA metabolic process RNA biosynthetic process nucleic acid biosynthetic process organic substance metabolic process negative regulation of cellular process regulation of RNA biosynthetic process negative regulation of macromolecule metabolic process regulation of biosynthetic process biological regulation regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process negative regulation of biosynthetic process cellular process cell death response to auxin response to organic substance response to stimulus response to hormone response to chemical response to endogenous stimulus auxin-activated signaling pathway cellular response to stimulus signaling hormone-mediated signaling pathway cellular response to auxin stimulus cell communication cellular response to endogenous stimulus cellular response to chemical stimulus cellular response to organic substance signal transduction cellular response to hormone stimulus developmental process multicellular organismal process plant organ development plant organ senescence multicellular organism development anatomical structure development leaf development leaf senescence shoot system development phyllome development system development	intracellular anatomical structure cytoplasm cellular anatomical entity membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR033389	AUX/IAA domain	Domain
A, B	IPR015300	DNA-binding pseudobarrel domain superfamily	Homologous Superfamily
A, B	IPR003340	B3 DNA binding domain	Domain
A, B	IPR000270	PB1 domain	Domain
A, B	IPR044835	Auxin response factor	Family
A, B	IPR010525	Auxin response factor domain	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.