4J4E

Structure of P51G Cyanovirin-N swapped trimer in the P212121 space group

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4j4ea_	All beta proteins	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	(Nostoc ellipsosporum ) [TaxId: 45916 ],	SCOPe (2.08)
B	d4j4eb_	All beta proteins	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	(Nostoc ellipsosporum ) [TaxId: 45916 ],	SCOPe (2.08)
C [auth E]	d4j4ee_	All beta proteins	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	(Nostoc ellipsosporum ) [TaxId: 45916 ],	SCOPe (2.08)
D [auth C]	d4j4ec_	All beta proteins	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	(Nostoc ellipsosporum ) [TaxId: 45916 ],	SCOPe (2.08)
E [auth D]	d4j4ed_	All beta proteins	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	(Nostoc ellipsosporum ) [TaxId: 45916 ],	SCOPe (2.08)
F	d4j4ef_	All beta proteins	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	Cyanovirin-N	(Nostoc ellipsosporum ) [TaxId: 45916 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Cyanovirin-N	8043158	3002001	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Cyanovirin-N	8043158	3002001	SCOP2B (2022-06-29)
C [auth E]	SCOP2B Superfamily	Cyanovirin-N	8043158	3002001	SCOP2B (2022-06-29)
D [auth C]	SCOP2B Superfamily	Cyanovirin-N	8043158	3002001	SCOP2B (2022-06-29)
E [auth D]	SCOP2B Superfamily	Cyanovirin-N	8043158	3002001	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Cyanovirin-N	8043158	3002001	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF08881	e4j4eA1	A: beta duplicates or obligate multimers	X: Cyanovirin-N (From Topology)	H: Cyanovirin-N (From Topology)	T: Cyanovirin-N	F: PF08881	ECOD (1.6)
B	PF08881	e4j4eB1	A: beta duplicates or obligate multimers	X: Cyanovirin-N (From Topology)	H: Cyanovirin-N (From Topology)	T: Cyanovirin-N	F: PF08881	ECOD (1.6)
C [auth E]	PF08881	e4j4eE1	A: beta duplicates or obligate multimers	X: Cyanovirin-N (From Topology)	H: Cyanovirin-N (From Topology)	T: Cyanovirin-N	F: PF08881	ECOD (1.6)
D [auth C]	PF08881	e4j4eC1	A: beta duplicates or obligate multimers	X: Cyanovirin-N (From Topology)	H: Cyanovirin-N (From Topology)	T: Cyanovirin-N	F: PF08881	ECOD (1.6)
E [auth D]	PF08881	e4j4eD1	A: beta duplicates or obligate multimers	X: Cyanovirin-N (From Topology)	H: Cyanovirin-N (From Topology)	T: Cyanovirin-N	F: PF08881	ECOD (1.6)
F	PF08881	e4j4eF1	A: beta duplicates or obligate multimers	X: Cyanovirin-N (From Topology)	H: Cyanovirin-N (From Topology)	T: Cyanovirin-N	F: PF08881	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.30.60.10	Mainly Beta	Roll	HIV-inactivating Protein, Cyanovirin-n	Cyanovirin-N	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C [auth E], D [auth C], E [auth D], A, B, C [auth E], D [auth C], E [auth D], F	PF08881	CVNH domain (CVNH)	CVNH domain	CyanoVirin-N Homology domains are found in the sugar-binding antiviral protein cyanovirin-N (CVN) as well as filamentous ascomycetes and in the fern Ceratopteris richardii.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C [auth E], D [auth C], E [auth D], A, B, C [auth E], D [auth C], E [auth D], F	Cyanovirin-N	binding carbohydrate binding	regulation of defense response regulation of response to biotic stimulus regulation of biological process biological process involved in interspecies interaction between organisms response to stimulus regulation of response to external stimulus response to other organism defense response biological regulation defense response to symbiont response to external stimulus response to biotic stimulus regulation of defense response to virus defense response to virus regulation of response to stimulus regulation of defense response regulation of response to biotic stimulus regulation of biological process biological process involved in interspecies interaction between organisms response to stimulus regulation of response to external stimulus response to other organism defense response biological regulation defense response to symbiont response to external stimulus response to biotic stimulus regulation of defense response to virus defense response to virus regulation of response to stimulus defense response to other organism response to stress regulation of response to stress response to external biotic stimulus response to virus	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C [auth E], D [auth C], E [auth D], A, B, C [auth E], D [auth C], E [auth D], F	IPR036673	Cyanovirin-N superfamily	Homologous Superfamily
A, B, C [auth E], D [auth C], E [auth D], A, B, C [auth E], D [auth C], E [auth D], F	IPR011058	Cyanovirin-N	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.