4IQG

Crystal structure of BPRO0239 oxidoreductase from Polaromonas sp. JS666 in NADP bound form

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A [auth C]	d4iqgc_	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	(Polaromonas sp. JS666 ) [TaxId: 296591 ],	SCOPe (2.08)
C [auth B]	d4iqgb_	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	(Polaromonas sp. JS666 ) [TaxId: 296591 ],	SCOPe (2.08)
D	d4iqgd1	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	(Polaromonas sp. JS666 ) [TaxId: 296591 ],	SCOPe (2.08)
D	d4iqgd2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Polaromonas sp. JS666 ) [TaxId: 296591 ],	SCOPe (2.08)
B [auth A]	d4iqga1	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	(Polaromonas sp. JS666 ) [TaxId: 296591 ],	SCOPe (2.08)
B [auth A]	d4iqga2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Polaromonas sp. JS666 ) [TaxId: 296591 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth C]	SCOP2B Superfamily	SDR-like	8066884	3000038	SCOP2B (2022-06-29)
C [auth B]	SCOP2B Superfamily	SDR-like	8066884	3000038	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	SDR-like	8066884	3000038	SCOP2B (2022-06-29)
B [auth A]	SCOP2 Family	Short-chain dehydrogenases/reductases SDR	8066883	4000029	SCOP2 (2022-06-29)
B [auth A]	SCOP2 Superfamily	SDR-like	8066884	3000038	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth C]	PF13561	e4iqgC2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NAD(P)-binding Rossmann-fold domains	F: PF13561	ECOD (1.6)
C [auth B]	PF13561	e4iqgB2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NAD(P)-binding Rossmann-fold domains	F: PF13561	ECOD (1.6)
D	PF13561	e4iqgD1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NAD(P)-binding Rossmann-fold domains	F: PF13561	ECOD (1.6)
B [auth A]	PF13561	e4iqgA1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NAD(P)-binding Rossmann-fold domains	F: PF13561	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth C]	3.40.50.720	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	NAD(P)-binding Rossmann-like Domain	CATH (4.3.0)
C [auth B]	3.40.50.720	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	NAD(P)-binding Rossmann-like Domain	CATH (4.3.0)
D	3.40.50.720	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	NAD(P)-binding Rossmann-like Domain	CATH (4.3.0)
B [auth A]	3.40.50.720	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	NAD(P)-binding Rossmann-like Domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth C], B [auth A], C [auth B], D	PF13561	Enoyl-(Acyl carrier protein) reductase (adh_short_C2)	Enoyl-(Acyl carrier protein) reductase	This domain is found in Enoyl-(Acyl carrier protein) reductases.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth C], B [auth A], C [auth B], D	Short-chain dehydrogenase/reductase SDR	oxidoreductase activity oxidoreductase activity, acting on CH-OH group of donors catalytic activity binding nucleoside phosphate binding organic cyclic compound binding nucleotide binding heterocyclic compound binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth C], B [auth A], C [auth B], D	IPR036291	NAD(P)-binding domain superfamily	Homologous Superfamily
A [auth C], B [auth A], C [auth B], D	IPR002347	Short-chain dehydrogenase/reductase SDR	Family
A [auth C], B [auth A], C [auth B], D	IPR020904	Short-chain dehydrogenase/reductase, conserved site	Conserved Site

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.