Annotations: 4IN3

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2B Superfamily	RBP8/CHS5 N-terminal domain-like	8093391	3002702	SCOP2B (2022-06-29)
A	SCOP2 Family	CHS5 N-terminal domain-like	8093390	4005015	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	RBP8/CHS5 N-terminal domain-like	8093391	3002702	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	TPR-like	8051938	3001345	SCOP2B (2022-06-29)
D	SCOP2 Family	ChAPs-like	8044664	4004067	SCOP2 (2022-06-29)
D	SCOP2 Superfamily	TPR-like	8051938	3001345	SCOP2 (2022-06-29)
D	SCOP2 Superfamily	ChAPs N-terminal domain-like	8051937	3002076	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C	PF16892	e4in3C1	A: beta barrels	X: OB-fold	H: HupF/HypC-like (From Topology)	T: HupF/HypC-like	F: PF16892	ECOD (1.6)
A	PF16892	e4in3A1	A: beta barrels	X: OB-fold	H: HupF/HypC-like (From Topology)	T: HupF/HypC-like	F: PF16892	ECOD (1.6)
B	PF09295	e4in3B2	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: PF09295	ECOD (1.6)
B	PF09295	e4in3B1	A: a+b two layers	X: N-terminal domain of chitin biosynthesis protein CHS6 (From Topology)	H: N-terminal domain of chitin biosynthesis protein CHS6 (From Topology)	T: N-terminal domain of chitin biosynthesis protein CHS6	F: PF09295	ECOD (1.6)
D	PF09295	e4in3D3	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: PF09295	ECOD (1.6)
D	PF09295	e4in3D2	A: a+b two layers	X: N-terminal domain of chitin biosynthesis protein CHS6 (From Topology)	H: N-terminal domain of chitin biosynthesis protein CHS6 (From Topology)	T: N-terminal domain of chitin biosynthesis protein CHS6	F: PF09295	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C	6.20.120.50	Special	Other non-globular	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)
A	6.20.120.50	Special	Other non-globular	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)
B	1.25.40.10	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	Tetratricopeptide repeat domain	CATH (4.3.0)
D	1.25.40.10	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	Tetratricopeptide repeat domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF16892	Chitin biosynthesis protein CHS5 N-terminus (CHS5_N)	Chitin biosynthesis protein CHS5 N-terminus	This domain is found at the N-terminus of fungal chitin biosynthesis protein CHS5. It functions as a dimerisation domain [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	Chitin biosynthesis protein CHS5	small GTPase binding protein binding binding enzyme binding GTPase binding protein dimerization activity	regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process cellular process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process Golgi to plasma membrane transport cellular localization post-Golgi vesicle-mediated transport transport localization within membrane establishment of localization vesicle-mediated transport vesicle-mediated transport to the plasma membrane localization Golgi vesicle transport sexual reproduction cellular developmental process reproductive process cellular component assembly involved in morphogenesis cell wall organization or biogenesis cell development cell wall organization spore wall biogenesis developmental process involved in reproduction meiotic cell cycle process ascospore wall assembly cellular component biogenesis cellular component organization cellular anatomical entity morphogenesis cellular component assembly spore wall assembly sexual sporulation cell differentiation anatomical structure development cell cycle cellular component organization or biogenesis cell cycle process developmental process fungal-type cell wall organization cell wall assembly sexual sporulation resulting in formation of a cellular spore reproductive process in single-celled organism meiotic cell cycle ascospore wall biogenesis fungal-type cell wall assembly sporulation resulting in formation of a cellular spore anatomical structure morphogenesis ascospore formation fungal-type cell wall organization or biogenesis cell wall biogenesis anatomical structure formation involved in morphogenesis sporulation fungal-type cell wall biogenesis external encapsulating structure organization cytoskeleton-dependent cytokinesis mitotic cytokinesis cytokinesis establishment or maintenance of cell polarity mitotic cell cycle establishment of cell polarity mitotic cell cycle process cell division cellular bud site selection catabolic process carbohydrate derivative metabolic process chitin metabolic process macromolecule catabolic process glucosamine-containing compound catabolic process cell wall chitin metabolic process amino sugar metabolic process glucosamine-containing compound metabolic process organonitrogen compound catabolic process carbohydrate derivative catabolic process organonitrogen compound metabolic process cell wall chitin catabolic process aminoglycan catabolic process cell wall macromolecule catabolic process amino sugar catabolic process aminoglycan metabolic process organic substance catabolic process chitin catabolic process cell wall macromolecule metabolic process protein localization establishment of protein localization nitrogen compound transport organic substance transport protein transport cellular macromolecule localization macromolecule localization conjugation with cellular fusion	membrane-bounded organelle protein-containing complex intracellular anatomical structure transport vesicle Golgi apparatus intracellular vesicle cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle trans-Golgi network transport vesicle cytoplasmic vesicle organelle exomer complex membrane-bounded organelle protein-containing complex intracellular anatomical structure transport vesicle Golgi apparatus intracellular vesicle cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle trans-Golgi network transport vesicle cytoplasmic vesicle organelle exomer complex clathrin-coated vesicle coated vesicle cytoplasm Golgi-associated vesicle vesicle membrane Golgi apparatus subcompartment organelle subcompartment trans-Golgi network cell projection mating projection cell tip mating projection tip cell pole plasma membrane bounded cell projection site of polarized growth cytosol
B, D	Protein BCH1	small GTPase binding protein binding binding enzyme binding GTPase binding	Golgi to plasma membrane transport cellular localization post-Golgi vesicle-mediated transport transport localization within membrane establishment of localization vesicle-mediated transport vesicle-mediated transport to the plasma membrane localization cellular process Golgi vesicle transport amino sugar biosynthetic process cellular biosynthetic process cell wall organization or biogenesis Golgi to plasma membrane transport cellular localization post-Golgi vesicle-mediated transport transport localization within membrane establishment of localization vesicle-mediated transport vesicle-mediated transport to the plasma membrane localization cellular process Golgi vesicle transport amino sugar biosynthetic process cellular biosynthetic process cell wall organization or biogenesis organonitrogen compound biosynthetic process carbohydrate derivative metabolic process chitin metabolic process cellular component biogenesis cell wall chitin metabolic process organic substance metabolic process amino sugar metabolic process organic substance biosynthetic process cellular component organization or biogenesis glucosamine-containing compound metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process fungal-type cell wall chitin biosynthetic process chitin biosynthetic process cellular metabolic process macromolecule biosynthetic process cell wall chitin biosynthetic process glucosamine-containing compound biosynthetic process fungal-type cell wall organization or biogenesis cell wall biogenesis biosynthetic process aminoglycan metabolic process aminoglycan biosynthetic process metabolic process macromolecule metabolic process fungal-type cell wall biogenesis cell wall macromolecule metabolic process protein localization establishment of protein localization nitrogen compound transport organic substance transport protein transport cellular macromolecule localization macromolecule localization	membrane-bounded organelle protein-containing complex intracellular anatomical structure transport vesicle Golgi apparatus intracellular vesicle cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle trans-Golgi network transport vesicle cytoplasmic vesicle organelle exomer complex membrane-bounded organelle protein-containing complex intracellular anatomical structure transport vesicle Golgi apparatus intracellular vesicle cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle trans-Golgi network transport vesicle cytoplasmic vesicle organelle exomer complex clathrin-coated vesicle coated vesicle cytoplasm Golgi-associated vesicle vesicle membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR003961	Fibronectin type III	Domain
A, C	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
A, C	IPR001357	BRCT domain	Domain
A, C	IPR031669	Fibronectin type III domain, fungi	Domain
A, C	IPR031673	Chitin biosynthesis protein Chs5, N-terminal	Domain
A, C	IPR036420	BRCT domain superfamily	Homologous Superfamily
A, C	IPR036116	Fibronectin type III superfamily	Homologous Superfamily
B, D	IPR011990	Tetratricopeptide-like helical domain superfamily	Homologous Superfamily
B, D	IPR015374	Chs5p-Arf1p binding	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.