Annotations: 4IIT

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2 Family	Ribonucleotide reductase-like	8083147	4000846	SCOP2 (2022-06-29)
C	SCOP2 Superfamily	Ferritin-like	8083148	3001658	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF05138	e4iitA1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Heme oxygenase/Ribonucleotide reductase	F: PF05138	ECOD (1.6)
B	PF06243	e4iitB1	A: a+b two layers	X: GP2-like	H: phenylacetate-CoA oxygenase subunit PaaB (From Topology)	T: phenylacetate-CoA oxygenase subunit PaaB	F: PF06243	ECOD (1.6)
C	PF05138	e4iitC1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Heme oxygenase/Ribonucleotide reductase	F: PF05138	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF05138	Phenylacetic acid catabolic protein (PaaA_PaaC)	Phenylacetic acid catabolic protein	This family includes proteins such as PaaA and PaaC that are part of a catabolic pathway of phenylacetic acid [1]. These proteins may form part of a dioxygenase complex.	Domain
B	PF06243	Phenylacetic acid degradation B (PaaB)	Phenylacetic acid degradation B	-	Family
C	PF05138	Phenylacetic acid catabolic protein (PaaA_PaaC)	Phenylacetic acid catabolic protein	This family includes proteins such as PaaA and PaaC that are part of a catabolic pathway of phenylacetic acid [1]. These proteins may form part of a dioxygenase complex.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Phenylacetate-CoA oxygenase subunit PaaA	oxidoreductase activity monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen phenylacetyl-CoA 1,2-epoxidase activity catalytic activity	cellular response to stimulus catabolic process response to stimulus oxoacid metabolic process organic acid catabolic process organic acid metabolic process response to xenobiotic stimulus cellular catabolic process organic substance metabolic process monocarboxylic acid catabolic process carboxylic acid catabolic process small molecule metabolic process benzene-containing compound metabolic process cellular response to xenobiotic stimulus cellular response to stimulus catabolic process response to stimulus oxoacid metabolic process organic acid catabolic process organic acid metabolic process response to xenobiotic stimulus cellular catabolic process organic substance metabolic process monocarboxylic acid catabolic process carboxylic acid catabolic process small molecule metabolic process benzene-containing compound metabolic process cellular response to xenobiotic stimulus cellular metabolic process carboxylic acid metabolic process xenobiotic catabolic process organic cyclic compound catabolic process xenobiotic metabolic process organic cyclic compound metabolic process cellular response to chemical stimulus response to chemical phenylacetate catabolic process metabolic process cellular process monocarboxylic acid metabolic process small molecule catabolic process organic substance catabolic process	-
B	Phenylacetate-CoA oxygenase subunit PaaB	-	-	-
C	Phenylacetate-CoA oxygenase subunit PaaC	-	cellular response to stimulus catabolic process response to stimulus oxoacid metabolic process organic acid catabolic process organic acid metabolic process response to xenobiotic stimulus cellular catabolic process organic substance metabolic process monocarboxylic acid catabolic process carboxylic acid catabolic process small molecule metabolic process benzene-containing compound metabolic process cellular response to xenobiotic stimulus cellular response to stimulus catabolic process response to stimulus oxoacid metabolic process organic acid catabolic process organic acid metabolic process response to xenobiotic stimulus cellular catabolic process organic substance metabolic process monocarboxylic acid catabolic process carboxylic acid catabolic process small molecule metabolic process benzene-containing compound metabolic process cellular response to xenobiotic stimulus cellular metabolic process carboxylic acid metabolic process xenobiotic catabolic process organic cyclic compound catabolic process xenobiotic metabolic process organic cyclic compound metabolic process cellular response to chemical stimulus response to chemical phenylacetate catabolic process metabolic process cellular process monocarboxylic acid metabolic process small molecule catabolic process organic substance catabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR012347	Ferritin-like	Homologous Superfamily
A	IPR009078	Ferritin-like superfamily	Homologous Superfamily
A	IPR007814	1,2-phenylacetyl-CoA epoxidase, subunit A/C	Family
A	IPR011881	1,2-phenylacetyl-CoA epoxidase, subunit A	Family
B	IPR009359	1,2-phenylacetyl-CoA epoxidase, subunit B	Family
B	IPR038693	Phenylacetyl-CoA epoxidase, subunit B	Homologous Superfamily
C	IPR012347	Ferritin-like	Homologous Superfamily
C	IPR009078	Ferritin-like superfamily	Homologous Superfamily
C	IPR007814	1,2-phenylacetyl-CoA epoxidase, subunit A/C	Family
C	IPR011882	1,2-phenylacetyl-CoA epoxidase, subunit C	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.