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Crystal structure of LC9-RNase H1, a type 1 RNase H with the type 2 active-site motif External Resource: Annotation Domain Annotation: SCOP2 Classification SCOP2 Database Homepage Chains Type Family Name Domain Identifier Family Identifier Provenance Source (Version) A SCOP2 Family Ribonuclease H-like 8075081 4000541 SCOP2 (2022-06-29) A SCOP2 Superfamily Ribonuclease H-like 8075082 3000143 SCOP2 (2022-06-29)
Chains Family Name Domain Identifier Architecture Possible Homology Homology Topology Family Provenance Source (Version) A PF00075 e4ibnA1 A: mixed a+b and a/b X: Ribonuclease H-like H: Ribonuclease H-like (From Topology) T: Ribonuclease H-like F: PF00075 ECOD (1.6)
Chains Accession Name Description Comments Source PF00075 RNase H (RNase_H) RNase H RNase H digests the RNA strand of an RNA/DNA hybrid. Important enzyme in retroviral replication cycle, and often found as a domain associated with reverse transcriptases. Structure is a mixed alpha+beta fold with three a/b/a layers. Domain
Chains Polymer Molecular Function Biological Process Cellular Component Ribonuclease H -