4GU3
Crystal structure of the T1L reovirus attachment protein sigma1 in complex with the GM2 glycan
Domain Annotation: ECOD Classification ECOD Database Homepage
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| A | Reo_sigma1_C | e4gu3A6 | A: beta sandwiches | X: Domain in virus attachment proteins (From Topology) | H: Domain in virus attachment proteins (From Topology) | T: Domain in virus attachment proteins | F: Reo_sigma1_C | ECOD (1.6) |
| A | Reo_sigma1_N | e4gu3A5 | A: beta duplicates or obligate multimers | X: Triple beta-spiral (From Topology) | H: Triple beta-spiral (From Topology) | T: Triple beta-spiral | F: Reo_sigma1_N | ECOD (1.6) |
| C | Reo_sigma1_C | e4gu3C4 | A: beta sandwiches | X: Domain in virus attachment proteins (From Topology) | H: Domain in virus attachment proteins (From Topology) | T: Domain in virus attachment proteins | F: Reo_sigma1_C | ECOD (1.6) |
| C | Reo_sigma1_N | e4gu3C3 | A: beta duplicates or obligate multimers | X: Triple beta-spiral (From Topology) | H: Triple beta-spiral (From Topology) | T: Triple beta-spiral | F: Reo_sigma1_N | ECOD (1.6) |
| B | Reo_sigma1_C | e4gu3B4 | A: beta sandwiches | X: Domain in virus attachment proteins (From Topology) | H: Domain in virus attachment proteins (From Topology) | T: Domain in virus attachment proteins | F: Reo_sigma1_C | ECOD (1.6) |
| B | Reo_sigma1_N | e4gu3B3 | A: beta duplicates or obligate multimers | X: Triple beta-spiral (From Topology) | H: Triple beta-spiral (From Topology) | T: Triple beta-spiral | F: Reo_sigma1_N | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
| Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
|---|---|---|---|---|---|---|
| A | 2.10.25.20 | Mainly Beta | Ribbon | Laminin | reovirus attachment protein sigma1 | CATH (4.3.0) |
| A | 2.60.90.20 | Mainly Beta | Sandwich | Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) | Virus attachment protein , globular domain | CATH (4.3.0) |
| C | 2.10.25.20 | Mainly Beta | Ribbon | Laminin | reovirus attachment protein sigma1 | CATH (4.3.0) |
| C | 2.60.90.20 | Mainly Beta | Sandwich | Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) | Virus attachment protein , globular domain | CATH (4.3.0) |
| B | 2.10.25.20 | Mainly Beta | Ribbon | Laminin | reovirus attachment protein sigma1 | CATH (4.3.0) |
| B | 2.60.90.20 | Mainly Beta | Sandwich | Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) | Virus attachment protein , globular domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
| Chains | Accession | Name | Description | Comments | Source |
|---|---|---|---|---|---|
| PF01664 | Reovirus viral attachment protein sigma 1 (Reo_sigma1) | Reovirus viral attachment protein sigma 1 | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
| Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
|---|---|---|---|---|
| Outer capsid protein sigma-1 | - |
|
InterPro: Protein Family Classification InterPro Database Homepage
| Chains | Accession | Name | Type |
|---|---|---|---|
| IPR008982 | Adenovirus pIV-like, attachment domain | Homologous Superfamily | |
| IPR002592 | Viral attachment sigma 1, reoviral | Family |
