Annotations: 4GCN

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00515,PF13424	e4gcnA1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: PF00515,PF13424	ECOD (1.6)
B	PF00515,PF13424	e4gcnB1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: PF00515,PF13424	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.25.40.10	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	Tetratricopeptide repeat domain	CATH (4.3.0)
B	1.25.40.10	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	Tetratricopeptide repeat domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00515	Tetratricopeptide repeat (TPR_1)	Tetratricopeptide repeat	-	Repeat
A, B	PF13424	Tetratricopeptide repeat (TPR_12)	Tetratricopeptide repeat	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Protein STI-1	Hsp90 protein binding protein binding binding heat shock protein binding molecular function inhibitor activity molecular function regulator activity ATPase inhibitor activity ATPase regulator activity Hsp70 protein binding protein-folding chaperone binding	multicellular organismal process determination of adult lifespan organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process protein maturation by protein folding primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process biosynthetic process protein folding organic substance biosynthetic process multicellular organismal process determination of adult lifespan organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process protein maturation by protein folding primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process biosynthetic process protein folding organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process response to stimulus response to stress response to heat response to abiotic stimulus response to temperature stimulus	protein-containing complex protein folding chaperone complex intracellular protein-containing complex intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR011990	Tetratricopeptide-like helical domain superfamily	Homologous Superfamily
A, B	IPR019734	Tetratricopeptide repeat	Repeat
A, B	IPR041243	STI1/HOP, DP domain	Domain
A, B	IPR006636	Heat shock chaperonin-binding	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.