4FGM

Crystal structure of the aminopeptidase N family protein Q5QTY1 from Idiomarina loihiensis. Northeast Structural Genomics Consortium Target IlR60.

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PDZ_2	e4fgmA8	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
A	COG3975	e4fgmA3	A: beta sandwiches	X: Baculovirus p35 protein-related (From Topology)	H: Baculovirus p35 protein-related (From Topology)	T: Baculovirus p35 protein-related	F: COG3975	ECOD (1.6)
A	Peptidase_M61	e4fgmA2	A: mixed a+b and a/b	X: Zincin-like	H: Metalloproteases (zincins) catalytic domain (From Topology)	T: Metalloproteases (zincins) catalytic domain	F: Peptidase_M61	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.40.3650	Mainly Beta	Sandwich	Immunoglobulin-like		CATH (4.3.0)
A	1.10.390.10	Mainly Alpha	Orthogonal Bundle	Neutral Protease	domain 2	CATH (4.3.0)
A	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF13180	PDZ domain (PDZ_2)	PDZ domain	-	Domain
A	PF05299	M61 glycyl aminopeptidase (Peptidase_M61)	M61 glycyl aminopeptidase	-	Family
A	PF17899	Peptidase M61 N-terminal domain (Peptidase_M61_N)	Peptidase M61 N-terminal domain	This domain is found at the N-terminus of Pfam:PF05299 and has a beta sandwich-like fold with similarity to the baculovirus p35 protein.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Aminopeptidase N family protein	cation binding ion binding binding metal ion binding small molecule binding peptidase activity catalytic activity, acting on a protein aminopeptidase activity hydrolase activity exopeptidase activity catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR027268	Peptidase M4/M1, CTD superfamily	Homologous Superfamily
A	IPR001478	PDZ domain	Domain
A	IPR007963	Peptidase M61, catalytic domain	Domain
A	IPR040756	Peptidase M61, N-terminal domain	Domain
A	IPR024191	Peptidase M61	Family
A	IPR036034	PDZ superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.