4FE4
Crystal structure of apo E. coli XylR
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00165 | e4fe4A5 | A: alpha arrays | X: HTH | H: HTH | T: tri-helical | F: PF00165 | ECOD (1.6) |
A | PF13377 | e4fe4A1 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: Periplasmic binding protein-like I | F: PF13377 | ECOD (1.6) |
A | PF22177 | e4fe4A6 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: Periplasmic binding protein-like I | F: PF22177 | ECOD (1.6) |
B | PF00165 | e4fe4B8 | A: alpha arrays | X: HTH | H: HTH | T: tri-helical | F: PF00165 | ECOD (1.6) |
B | PF13377 | e4fe4B1 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: Periplasmic binding protein-like I | F: PF13377 | ECOD (1.6) |
B | PF22177 | e4fe4B4 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: Periplasmic binding protein-like I | F: PF22177 | ECOD (1.6) |
C | PF00165 | e4fe4C8 | A: alpha arrays | X: HTH | H: HTH | T: tri-helical | F: PF00165 | ECOD (1.6) |
C | PF13377 | e4fe4C1 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: Periplasmic binding protein-like I | F: PF13377 | ECOD (1.6) |
C | PF22177 | e4fe4C4 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: Periplasmic binding protein-like I | F: PF22177 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.2300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Response regulator | CATH (4.3.0) |
A | 1.10.10.60 | Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Homeodomain-like | CATH (4.3.0) |
B | 3.40.50.2300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Response regulator | CATH (4.3.0) |
B | 1.10.10.60 | Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Homeodomain-like | CATH (4.3.0) |
C | 3.40.50.2300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Response regulator | CATH (4.3.0) |
C | 1.10.10.60 | Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Homeodomain-like | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00165 | Bacterial regulatory helix-turn-helix proteins, AraC family (HTH_AraC) | Bacterial regulatory helix-turn-helix proteins, AraC family | In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (Pfam:PF00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind ove ... | Domain | |
PF13377 | Periplasmic binding protein-like domain (Peripla_BP_3) | Periplasmic binding protein-like domain | This domain is found in a variety of transcriptional regulatory proteins. It is related to bacterial periplasmic binding proteins, although this domain is unlikely to be found in the periplasm. This domain acts as a sensor binding small molecule liga ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR046335 | Transcriptional regulator LacI/GalR-like, sensor domain | Domain | |
IPR018060 | DNA binding HTH domain, AraC-type | Domain | |
IPR028082 | Periplasmic binding protein-like I | Homologous Superfamily | |
IPR018062 | HTH domain AraC-type, conserved site | Conserved Site | |
IPR020449 | Transcription regulator HTH, AraC- type | Family | |
IPR009057 | Homeobox-like domain superfamily | Homologous Superfamily |