4E2Q

Crystal Structure of (S)-Ureidoglycine Aminohydrolase from Arabidopsis thaliana

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4e2qa_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
B	d4e2qb_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
C	d4e2qc_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
D	d4e2qd_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
E	d4e2qe_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
F	d4e2qf_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
G	d4e2qg_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
H	d4e2qh_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
I	d4e2qi_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
J	d4e2qj_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
K	d4e2qk_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
L	d4e2ql_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
M	d4e2qm_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
N	d4e2qn_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
O	d4e2qo_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
P	d4e2qp_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	mouse-ear cress, thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	AllE-like	8083126	4000965	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	RmlC-like cupins	8083127	3001825	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
O	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)
P	SCOP2B Superfamily	RmlC-like cupins	8083127	3001825	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Cupin_3	e4e2qA2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
A	Cupin_2	e4e2qA1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
B	Cupin_3	e4e2qB1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
B	Cupin_2	e4e2qB2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
C	Cupin_3	e4e2qC2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
C	Cupin_2	e4e2qC1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
D	Cupin_3	e4e2qD2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
D	Cupin_2	e4e2qD1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
E	Cupin_3	e4e2qE2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
E	Cupin_2	e4e2qE1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
F	Cupin_3	e4e2qF2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
F	Cupin_2	e4e2qF1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
G	Cupin_3	e4e2qG1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
G	Cupin_2	e4e2qG2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
H	Cupin_3	e4e2qH1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
H	Cupin_2	e4e2qH2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
I	Cupin_3	e4e2qI1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
I	Cupin_2	e4e2qI2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
J	Cupin_3	e4e2qJ2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
J	Cupin_2	e4e2qJ1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
K	Cupin_3	e4e2qK1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
K	Cupin_2	e4e2qK2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
L	Cupin_3	e4e2qL1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
L	Cupin_2	e4e2qL2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
M	Cupin_3	e4e2qM1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
M	Cupin_2	e4e2qM2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
N	Cupin_3	e4e2qN2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
N	Cupin_2	e4e2qN1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
O	Cupin_3	e4e2qO1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
O	Cupin_2	e4e2qO2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)
P	Cupin_3	e4e2qP1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_3	ECOD (1.6)
P	Cupin_2	e4e2qP2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
B	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
C	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
D	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
E	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
F	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
G	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
H	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
I	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
J	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
K	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
L	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
M	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
N	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
O	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
P	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	PF07883	Cupin domain (Cupin_2)	Cupin domain	This family represents the conserved barrel domain of the 'cupin' superfamily [1] ('cupa' is the Latin term for a small barrel).	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	Ureidoglycine aminohydrolase	transcription regulator activity DNA-binding transcription factor activity ureidoglycine aminohydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines hydrolase activity catalytic activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds cation binding ion binding binding metal ion binding small molecule binding	regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process cellular process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process organonitrogen compound catabolic process allantoin metabolic process catabolic process organonitrogen compound metabolic process organic cyclic compound catabolic process amide catabolic process amide metabolic process allantoin catabolic process organic substance catabolic process purine nucleobase metabolic process purine-containing compound catabolic process purine nucleobase catabolic process purine-containing compound metabolic process nucleobase catabolic process nucleobase-containing small molecule metabolic process nucleobase metabolic process small molecule metabolic process ureide metabolic process ureide catabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol membrane-bounded organelle intracellular organelle organelle endoplasmic reticulum intracellular membrane-bounded organelle endomembrane system

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR044704	(S)-ureidoglycine aminohydrolase, N-terminal cupin domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR044697	(S)-ureidoglycine aminohydrolase, C-terminal cupin domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR017627	(S)-ureidoglycine aminohydrolase	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR013096	Cupin 2, conserved barrel	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR014710	RmlC-like jelly roll fold	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR011051	RmlC-like cupin domain superfamily	Homologous Superfamily

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4E2Q

Crystal Structure of (S)-Ureidoglycine Aminohydrolase from Arabidopsis thaliana

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Domain Annotation: ECOD Classification ECOD Database Homepage

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage