Annotations: 4D0A

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth B]	PF00999	e4d0aB1	A: alpha complex topology	X: Cation-proton antiporter	H: Cation-proton antiporter (CPA) (From Topology)	T: Cation-proton antiporter (CPA)	F: PF00999	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth B]	PF00999	Sodium/hydrogen exchanger family (Na_H_Exchanger)	Sodium/hydrogen exchanger family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth B]	NA(+)/H(+) ANTIPORTER 1	antiporter activity active transmembrane transporter activity transporter activity transmembrane transporter activity secondary active transmembrane transporter activity identical protein binding protein binding binding	transport proton transmembrane transport monoatomic ion transmembrane transport inorganic ion transmembrane transport establishment of localization inorganic cation transmembrane transport transmembrane transport monoatomic cation transmembrane transport localization monoatomic ion transport cellular process monoatomic cation transport sodium ion transport metal ion transport	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth B]	IPR006153	Cation/H+ exchanger	Domain
A [auth B]	IPR038770	Sodium/solute symporter superfamily	Homologous Superfamily

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A [auth B]	OPM	Transmembrane	Alpha-helical polytopic	Monovalent cation-proton antiporter	Sodium-proton antiporter 1

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A [auth B]	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A [auth B]	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A [auth B]	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Antiporters	NhaP1 Na⁺/H⁺ antiporter, pH 8

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.