4BSP
Crystal structure of R-spondin 1 (Fu1Fu2) - Holmium soak
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d4bspa_ | Small proteins | Knottins (small inhibitors, toxins, lectins) | Growth factor receptor domain | Growth factor receptor domain | Stem cell growth factor R-spondin-1 (Rspo1) Furin (Fu1Fu2) domain | HUMAN (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 2.10.220.10 | Mainly Beta | Ribbon | Hormone Receptor, Insulin-like Growth Factor Receptor 1 | Chain A domain 2 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF15913 | Furin-like repeat, cysteine-rich (Furin-like_2) | Furin-like repeat, cysteine-rich | The furin-like cysteine rich region has been found in a variety of proteins from eukaryotes that are involved in the mechanism of signal transduction by receptor tyrosine kinases, which involves receptor aggregation. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR000884 | Thrombospondin type-1 (TSP1) repeat | Repeat | |
IPR043601 | R-spondin, Fu-CRD domain | Domain | |
IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily | Homologous Superfamily | |
IPR006212 | Furin-like repeat | Repeat | |
IPR009030 | Growth factor receptor cysteine-rich domain superfamily | Homologous Superfamily |