4AEX
HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 2.4 ANGSTROM in a primitive orthorhombic space group
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d4aexa_ | Multi-domain proteins (alpha and beta) | DNA/RNA polymerases | DNA/RNA polymerases | RNA-dependent RNA-polymerase | automated matches | HCV (Hepacivirus hominis ) [TaxId: 3052230 ], | SCOPe (2.08) |
B | d4aexb_ | Multi-domain proteins (alpha and beta) | DNA/RNA polymerases | DNA/RNA polymerases | RNA-dependent RNA-polymerase | automated matches | HCV (Hepacivirus hominis ) [TaxId: 3052230 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00998 | e4aexA1 | A: alpha bundles | X: helical bundle domain in reverse transcriptase-like polymerases (From Topology) | H: helical bundle domain in reverse transcriptase-like polymerases (From Topology) | T: helical bundle domain in reverse transcriptase-like polymerases | F: PF00998 | ECOD (1.6) |
A | PF00998 | e4aexA2 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: PF00998 | ECOD (1.6) |
B | PF00998 | e4aexB1 | A: alpha bundles | X: helical bundle domain in reverse transcriptase-like polymerases (From Topology) | H: helical bundle domain in reverse transcriptase-like polymerases (From Topology) | T: helical bundle domain in reverse transcriptase-like polymerases | F: PF00998 | ECOD (1.6) |
B | PF00998 | e4aexB2 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: PF00998 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00998 | Viral RNA dependent RNA polymerase (RdRP_3) | Viral RNA dependent RNA polymerase | - | Family |