Annotations: 4AAS

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00118	e4aasA1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
A	PF00118	e4aasA3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
A	F_UNCLASSIFIED	e4aasA2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF00118	e4aasB1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
B	PF00118	e4aasB3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
B	F_UNCLASSIFIED	e4aasB2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
C	PF00118	e4aasC1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
C	PF00118	e4aasC3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
C	F_UNCLASSIFIED	e4aasC2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
D	PF00118	e4aasD1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
D	PF00118	e4aasD3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
D	F_UNCLASSIFIED	e4aasD2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
E	PF00118	e4aasE1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
E	PF00118	e4aasE3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
E	F_UNCLASSIFIED	e4aasE2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
F	PF00118	e4aasF1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
F	PF00118	e4aasF3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
F	F_UNCLASSIFIED	e4aasF2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
G	PF00118	e4aasG1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
G	PF00118	e4aasG3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
G	F_UNCLASSIFIED	e4aasG2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
H	PF00118	e4aasH1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
H	PF00118	e4aasH3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
H	F_UNCLASSIFIED	e4aasH2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
I	PF00118	e4aasI1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
I	PF00118	e4aasI3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
I	F_UNCLASSIFIED	e4aasI2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
J	PF00118	e4aasJ1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
J	PF00118	e4aasJ3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
J	F_UNCLASSIFIED	e4aasJ2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
K	PF00118	e4aasK1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
K	PF00118	e4aasK3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
K	F_UNCLASSIFIED	e4aasK2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
L	PF00118	e4aasL1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
L	PF00118	e4aasL3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
L	F_UNCLASSIFIED	e4aasL2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
M	PF00118	e4aasM2	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
M	PF00118	e4aasM1	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
M	F_UNCLASSIFIED	e4aasM3	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
N	PF00118	e4aasN2	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
N	PF00118	e4aasN1	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
N	F_UNCLASSIFIED	e4aasN3	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	60 KDA CHAPERONIN	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding unfolded protein binding protein binding isomerase activity catalytic activity pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides ATP-dependent activity ATP-dependent protein folding chaperone protein folding chaperone identical protein binding	protein refolding organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein refolding organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process chaperone cofactor-dependent protein refolding chaperone-mediated protein folding 'de novo' protein folding 'de novo' post-translational protein folding virion assembly viral process viral life cycle response to stimulus response to radiation response to abiotic stimulus response to stress response to heat response to temperature stimulus	membrane cellular anatomical entity protein-containing complex chaperonin ATPase complex intracellular anatomical structure protein folding chaperone complex GroEL-GroES complex cytoplasm cytosol intracellular protein-containing complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR001844	Chaperonin Cpn60/GroEL	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR018370	Chaperonin Cpn60, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family