Annotations: 3ZUZ

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	SHQ1 C-terminal domain-like	8103589	3002783	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF04925	e3zuzA1	A: alpha arrays	X: SHQ1 C-terminal domain-like	H: SHQ1 C-terminal domain (From Topology)	T: SHQ1 C-terminal domain	F: PF04925	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF04925	SHQ1 protein, Shq1 domain (SHQ1)	SHQ1 protein, Shq1 domain	This domain is found at the C-terminal end of Protein SHQ1 homolog from humans and similar eukaryotic proteins. SHQ1 is a factor required for the biogenesis and assembly of H/ACA small nucleolar ribonucleoparticle (snoRNP), which are essential for ri ...	This domain is found at the C-terminal end of Protein SHQ1 homolog from humans and similar eukaryotic proteins. SHQ1 is a factor required for the biogenesis and assembly of H/ACA small nucleolar ribonucleoparticle (snoRNP), which are essential for ribosomal RNA and telomerase RNA processing and metabolism. This protein contains two domains: an N-terminal CS or HSP20-like domain (Pfam:PF21413) and a C-terminal region called the Shq1 domain (this entry). This domain adopts a mostly helical structure that consists of 17 alpha-helices and two short beta-strands [1,2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	PROTEIN SHQ1	unfolded protein binding protein binding binding	ribonucleoprotein complex biogenesis box H/ACA snoRNP assembly protein-containing complex organization small nucleolar ribonucleoprotein complex assembly protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular process cellular component organization or biogenesis	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen intracellular organelle nucleoplasm organelle lumen organelle nuclear lumen

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR007052	CS domain	Domain
A	IPR007009	Shq1, C-terminal domain	Domain
A	IPR048696	SHQ1-like, CS domain	Domain
A	IPR008978	HSP20-like chaperone	Homologous Superfamily
A	IPR039742	Protein Shq1	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.