3ZK4

Structure of purple acid phosphatase PPD1 isolated from yellow lupin (Lupinus luteus) seeds

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF16656	e3zk4A1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF16656	ECOD (1.6)
A	PF17808	e3zk4A2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF17808	ECOD (1.6)
A	PF00149,PF14008	e3zk4A3	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Metallo-dependent phosphatases (From Topology)	T: Metallo-dependent phosphatases	F: PF00149,PF14008	ECOD (1.6)
B	PF16656	e3zk4B2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF16656	ECOD (1.6)
B	PF17808	e3zk4B3	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF17808	ECOD (1.6)
B	PF00149,PF14008	e3zk4B1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Metallo-dependent phosphatases (From Topology)	T: Metallo-dependent phosphatases	F: PF00149,PF14008	ECOD (1.6)
C	PF16656	e3zk4C1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF16656	ECOD (1.6)
C	PF17808	e3zk4C2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF17808	ECOD (1.6)
C	PF00149,PF14008	e3zk4C3	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Metallo-dependent phosphatases (From Topology)	T: Metallo-dependent phosphatases	F: PF00149,PF14008	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF00149	Calcineurin-like phosphoesterase (Metallophos)	Calcineurin-like phosphoesterase	This family includes a diverse range of phosphoesterases [1], including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD Swiss:P13457 or ...	This family includes a diverse range of phosphoesterases [1], including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD Swiss:P13457 or yeast MRE11 Swiss:P32829. The most conserved regions in this superfamily centre around the metal chelating residues.	Domain
A, B, C	PF17808	Fn3-like domain from Purple Acid Phosphatase (fn3_PAP)	Fn3-like domain from Purple Acid Phosphatase	This entry represents an N-terminal Fn3-like domain found at the N-terminus of purple acid phosphatase enzymes [1].	Domain
A, B, C	PF16656	Purple acid Phosphatase, N-terminal domain (Pur_ac_phosph_N)	Purple acid Phosphatase, N-terminal domain	This domain is found at the N-terminus of Purple acid phosphatase proteins.	Domain
A, B, C	PF14008	Iron/zinc purple acid phosphatase-like protein C (Metallophos_C)	Iron/zinc purple acid phosphatase-like protein C	This domain is found at the C-terminus of Purple acid phosphatase proteins.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	DIPHOSPHONUCLEOTIDE PHOSPHATASE 1	phosphoric ester hydrolase activity acid phosphatase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity catalytic activity cation binding ion binding binding metal ion binding small molecule binding	-	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR004843	Calcineurin-like phosphoesterase domain, ApaH type	Domain
A, B, C	IPR025733	Iron/zinc purple acid phosphatase-like C-terminal domain	Domain
A, B, C	IPR040974	Purple acid phosphatase, Fn3-like domain	Domain
A, B, C	IPR041792	Purple acid phosphatase, metallophosphatase domain	Domain
A, B, C	IPR008963	Purple acid phosphatase-like, N-terminal	Homologous Superfamily
A, B, C	IPR015914	Purple acid phosphatase, N-terminal	Domain
A, B, C	IPR029052	Metallo-dependent phosphatase-like	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.