3X27

Structure of McbB in complex with tryptophan

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AF_UNCLASSIFIEDe3x27A1 A: beta barrelsX: Cyclophilin-like (From Topology)H: Cyclophilin-like (From Topology)T: Cyclophilin-likeF: F_UNCLASSIFIEDECOD (1.6)
APF18631e3x27A2 A: alpha bundlesX: Four-helical up-and-down bundleH: Cucumopine synthase helical bundle domain (From Topology)T: Cucumopine synthase helical bundle domainF: PF18631ECOD (1.6)
BF_UNCLASSIFIEDe3x27B1 A: beta barrelsX: Cyclophilin-like (From Topology)H: Cyclophilin-like (From Topology)T: Cyclophilin-likeF: F_UNCLASSIFIEDECOD (1.6)
BPF18631e3x27B2 A: alpha bundlesX: Four-helical up-and-down bundleH: Cucumopine synthase helical bundle domain (From Topology)T: Cucumopine synthase helical bundle domainF: PF18631ECOD (1.6)
CF_UNCLASSIFIEDe3x27C2 A: beta barrelsX: Cyclophilin-like (From Topology)H: Cyclophilin-like (From Topology)T: Cyclophilin-likeF: F_UNCLASSIFIEDECOD (1.6)
CPF18631e3x27C1 A: alpha bundlesX: Four-helical up-and-down bundleH: Cucumopine synthase helical bundle domain (From Topology)T: Cucumopine synthase helical bundle domainF: PF18631ECOD (1.6)
DF_UNCLASSIFIEDe3x27D1 A: beta barrelsX: Cyclophilin-like (From Topology)H: Cyclophilin-like (From Topology)T: Cyclophilin-likeF: F_UNCLASSIFIEDECOD (1.6)
DPF18631e3x27D2 A: alpha bundlesX: Four-helical up-and-down bundleH: Cucumopine synthase helical bundle domain (From Topology)T: Cucumopine synthase helical bundle domainF: PF18631ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.40.100.20 Mainly Beta Beta Barrel Cyclophilin CATH (4.3.0)
B2.40.100.20 Mainly Beta Beta Barrel Cyclophilin CATH (4.3.0)
C2.40.100.20 Mainly Beta Beta Barrel Cyclophilin CATH (4.3.0)
D2.40.100.20 Mainly Beta Beta Barrel Cyclophilin CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF18631Cucumopine synthase C-terminal helical bundle domain (Cucumopine_C)Cucumopine synthase C-terminal helical bundle domainMcbB from Marinactinospora thermotolerans is an enzyme that catalyzes the Pictet-Spengler (PS) reaction of L-tryptophan and oxaloacetaldehyde to produce the betaC scaffold of marinacarbolines. This is the C-terminal domain composed of 5 bundled alpha ...McbB from Marinactinospora thermotolerans is an enzyme that catalyzes the Pictet-Spengler (PS) reaction of L-tryptophan and oxaloacetaldehyde to produce the betaC scaffold of marinacarbolines. This is the C-terminal domain composed of 5 bundled alpha helices. It is weakly similar to the signal transduction histidine-protein kinase BarA from E. coli and the DNA endonuclease I-MsoI from Monomastix sp [1].
Domain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D
IPR040602Cucumopine synthase, C-terminal helical bundle domainDomain