3WTN

Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with Desnitro-imidacloprid

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3wtna1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
A	d3wtna2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
B	d3wtnb1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
B	d3wtnb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
C	d3wtnc1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
C	d3wtnc2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
D	d3wtnd1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
D	d3wtnd2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
E	d3wtne1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
E	d3wtne2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
F	d3wtnf1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
F	d3wtnf2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
G	d3wtng1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
G	d3wtng2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
H	d3wtnh1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
H	d3wtnh2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
I	d3wtni1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
I	d3wtni2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
J	d3wtnj1	All beta proteins	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	automated matches	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)
J	d3wtnj2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Great pond snail (Lymnaea stagnalis ) [TaxId: 6523 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Nicotinic receptor ligand binding domain-like	8035210	3000369	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Neur_chan_LBD	e3wtnA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
B	Neur_chan_LBD	e3wtnB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
C	Neur_chan_LBD	e3wtnC1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
D	Neur_chan_LBD	e3wtnD1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
E	Neur_chan_LBD	e3wtnE1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
F	Neur_chan_LBD	e3wtnF1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
G	Neur_chan_LBD	e3wtnG1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
H	Neur_chan_LBD	e3wtnH1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
I	Neur_chan_LBD	e3wtnI1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
J	Neur_chan_LBD	e3wtnJ1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
B	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
C	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
D	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
E	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
F	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
G	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
H	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
I	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)
J	2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein	Chain: A,	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	PF02931	Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD)	Neurotransmitter-gated ion-channel ligand binding domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	Acetylcholine-binding protein	ligand-gated channel activity ligand-gated monoatomic ion channel activity extracellular ligand-gated monoatomic ion channel activity passive transmembrane transporter activity gated channel activity monoatomic ion channel activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity molecular transducer activity transmembrane signaling receptor activity signaling receptor activity	-	synaptic cleft extracellular region cellular anatomical entity membrane synapse cell junction

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	IPR007110	Immunoglobulin-like domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	IPR006201	Neurotransmitter-gated ion-channel	Family