3VSI

Crystal structure of native 1,6-APD (2-Animophenol-1,6-dioxygenase) complex with 4-Nitrocatechol

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	LigB	e3vsiA1	A: a/b three-layered sandwiches	X: LigB-like (From Topology)	H: LigB-like (From Topology)	T: LigB-like	F: LigB	ECOD (1.6)
C	LigB	e3vsiC1	A: a/b three-layered sandwiches	X: LigB-like (From Topology)	H: LigB-like (From Topology)	T: LigB-like	F: LigB	ECOD (1.6)
B	LigB	e3vsiB1	A: a/b three-layered sandwiches	X: LigB-like (From Topology)	H: LigB-like (From Topology)	T: LigB-like	F: LigB	ECOD (1.6)
D	LigB	e3vsiD1	A: a/b three-layered sandwiches	X: LigB-like (From Topology)	H: LigB-like (From Topology)	T: LigB-like	F: LigB	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.830.10	Alpha Beta	3-Layer(aba) Sandwich	Protocatechuate 4,5-dioxygenase	Chain B	CATH (4.3.0)
C	3.40.830.10	Alpha Beta	3-Layer(aba) Sandwich	Protocatechuate 4,5-dioxygenase	Chain B	CATH (4.3.0)
B	3.40.830.10	Alpha Beta	3-Layer(aba) Sandwich	Protocatechuate 4,5-dioxygenase	Chain B	CATH (4.3.0)
D	3.40.830.10	Alpha Beta	3-Layer(aba) Sandwich	Protocatechuate 4,5-dioxygenase	Chain B	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF02900	Catalytic LigB subunit of aromatic ring-opening dioxygenase (LigB)	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	Domain
B, D	PF02900	Catalytic LigB subunit of aromatic ring-opening dioxygenase (LigB)	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	2-amino-5-chlorophenol 1,6-dioxygenase alpha subunit	cation binding transition metal ion binding iron ion binding ion binding binding ferrous iron binding metal ion binding small molecule binding oxidoreductase activity catalytic activity dioxygenase activity	-	-
B, D	2-amino-5-chlorophenol 1,6-dioxygenase beta subunit	cation binding transition metal ion binding iron ion binding ion binding binding ferrous iron binding metal ion binding small molecule binding oxidoreductase activity catalytic activity dioxygenase activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR004183	Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B	Domain
B, D	IPR034943	2-aminophenol 1,6-dioxygenase, beta subunit	Family
B, D	IPR004183	Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.