Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth D]PF21176e3ve5D3 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: SAM domain-likeF: PF21176ECOD (1.6)
A [auth D]PF13662,PF21175e3ve5D2 A: a/b three-layered sandwichesX: HAD domain-likeH: HAD domain-relatedT: Toprim domainF: PF13662,PF21175ECOD (1.6)
A [auth D]PF02132e3ve5D1 A: few secondary structure elementsX: RING/U-box-likeH: RING/U-box-likeT: RING/U-boxF: PF02132ECOD (1.6)
B [auth A]PF21176e3ve5A2 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: SAM domain-likeF: PF21176ECOD (1.6)
B [auth A]PF13662,PF21175e3ve5A3 A: a/b three-layered sandwichesX: HAD domain-likeH: HAD domain-relatedT: Toprim domainF: PF13662,PF21175ECOD (1.6)
B [auth A]PF02132e3ve5A1 A: few secondary structure elementsX: RING/U-box-likeH: RING/U-box-likeT: RING/U-boxF: PF02132ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth D],
B [auth A]
PF21176RecR, helix-hairpin-helix (RecR_HhH)RecR, helix-hairpin-helix- Motif
A [auth D],
B [auth A]
PF21175RecR, C-terminal (RecR_C)RecR, C-terminalThe bacterial protein RecR is an important regulator in the RecFOR homologous recombination pathway during DNA repair. It acts with RecF and RecO forming a complex that facilitates the loading of RecA onto ssDNA. RecR is a zinc metalloprotein consist ...The bacterial protein RecR is an important regulator in the RecFOR homologous recombination pathway during DNA repair. It acts with RecF and RecO forming a complex that facilitates the loading of RecA onto ssDNA. RecR is a zinc metalloprotein consisting of a N-terminal helix-hairpin-helix (HhH) motif, a middle region containing a zinc finger motif (Pfam:PF02132) and a Toprim domain (Pfam:PF13662) and a C-terminal domain comprising a Walker B motif and a C-terminal helix [1,2]. This is the C-terminal domain of RecR, which has a divergent Walker B motif, suggesting a nucleotide binding site [1,2].
Domain
A [auth D],
B [auth A]
PF02132RecR, Cys4-zinc finger motif (RecR_ZnF)RecR, Cys4-zinc finger motif- Motif
A [auth D],
B [auth A]
PF13662Toprim domain (Toprim_4)Toprim domainThe toprim domain is found in a wide variety of enzymes involved in nucleic acid manipulation [1].Domain