3U4J

Crystal structure of NAD-dependent aldehyde dehydrogenase from Sinorhizobium meliloti

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3u4ja1	Alpha and beta proteins (a/b)	ALDH-like	ALDH-like	automated matches	automated matches	Ensifer meliloti (Sinorhizobium meliloti ) [TaxId: 382 ],	SCOPe (2.08)
A	d3u4ja2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Ensifer meliloti (Sinorhizobium meliloti ) [TaxId: 382 ],	SCOPe (2.08)
B	d3u4jb_	Alpha and beta proteins (a/b)	ALDH-like	ALDH-like	automated matches	automated matches	Ensifer meliloti (Sinorhizobium meliloti ) [TaxId: 382 ],	SCOPe (2.08)
C	d3u4jc1	Alpha and beta proteins (a/b)	ALDH-like	ALDH-like	automated matches	automated matches	Ensifer meliloti (Sinorhizobium meliloti ) [TaxId: 382 ],	SCOPe (2.08)
C	d3u4jc2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Ensifer meliloti (Sinorhizobium meliloti ) [TaxId: 382 ],	SCOPe (2.08)
D	d3u4jd_	Alpha and beta proteins (a/b)	ALDH-like	ALDH-like	automated matches	automated matches	Ensifer meliloti (Sinorhizobium meliloti ) [TaxId: 382 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	ALDH-like	8072416	4000806	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	ALDH-like	8072417	3001479	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	ALDH-like	8072417	3001479	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	ALDH-like	8072417	3001479	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	ALDH-like	8072417	3001479	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00171	e3u4jA1	A: a/b three-layered sandwiches	X: ALDH-like (From Topology)	H: ALDH-like (From Topology)	T: ALDH-like	F: PF00171	ECOD (1.6)
B	PF00171	e3u4jB2	A: a/b three-layered sandwiches	X: ALDH-like (From Topology)	H: ALDH-like (From Topology)	T: ALDH-like	F: PF00171	ECOD (1.6)
C	PF00171	e3u4jC2	A: a/b three-layered sandwiches	X: ALDH-like (From Topology)	H: ALDH-like (From Topology)	T: ALDH-like	F: PF00171	ECOD (1.6)
D	PF00171	e3u4jD2	A: a/b three-layered sandwiches	X: ALDH-like (From Topology)	H: ALDH-like (From Topology)	T: ALDH-like	F: PF00171	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.605.10	Alpha Beta	3-Layer(aba) Sandwich	Aldehyde Dehydrogenase	Chain A, domain 1	CATH (4.3.0)
A	3.40.309.10	Alpha Beta	3-Layer(aba) Sandwich	Aldehyde Dehydrogenase	Chain A, domain 2	CATH (4.3.0)
B	3.40.605.10	Alpha Beta	3-Layer(aba) Sandwich	Aldehyde Dehydrogenase	Chain A, domain 1	CATH (4.3.0)
B	3.40.309.10	Alpha Beta	3-Layer(aba) Sandwich	Aldehyde Dehydrogenase	Chain A, domain 2	CATH (4.3.0)
C	3.40.605.10	Alpha Beta	3-Layer(aba) Sandwich	Aldehyde Dehydrogenase	Chain A, domain 1	CATH (4.3.0)
C	3.40.309.10	Alpha Beta	3-Layer(aba) Sandwich	Aldehyde Dehydrogenase	Chain A, domain 2	CATH (4.3.0)
D	3.40.605.10	Alpha Beta	3-Layer(aba) Sandwich	Aldehyde Dehydrogenase	Chain A, domain 1	CATH (4.3.0)
D	3.40.309.10	Alpha Beta	3-Layer(aba) Sandwich	Aldehyde Dehydrogenase	Chain A, domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00171	Aldehyde dehydrogenase family (Aldedh)	Aldehyde dehydrogenase family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	NAD-dependent aldehyde dehydrogenase	oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors catalytic activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor cation binding ion binding binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR015590	Aldehyde dehydrogenase domain	Domain
A, B, C, D	IPR016161	Aldehyde/histidinol dehydrogenase	Homologous Superfamily
A, B, C, D	IPR016162	Aldehyde dehydrogenase, N-terminal	Homologous Superfamily
A, B, C, D	IPR016163	Aldehyde dehydrogenase, C-terminal	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.