3TNX
Structure of the precursor of a thermostable variant of papain at 2.6 Angstroem resolution
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Cysteine proteinases | 8036216 | 3001808 | SCOP2B (2022-06-29) |
B [auth C] | SCOP2B Superfamily | Cysteine proteinases | 8036216 | 3001808 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Inhibitor_I29 | e3tnxA2 | A: alpha arrays | X: Peptidase inhibitors family I29 (From Topology) | H: Peptidase inhibitors family I29 (From Topology) | T: Peptidase inhibitors family I29 | F: Inhibitor_I29 | ECOD (1.6) |
A | Peptidase_C1 | e3tnxA1 | A: a+b complex topology | X: Cysteine proteinases-like | H: Cysteine proteinases (From Topology) | T: Cysteine proteinases | F: Peptidase_C1 | ECOD (1.6) |
B [auth C] | Inhibitor_I29 | e3tnxC2 | A: alpha arrays | X: Peptidase inhibitors family I29 (From Topology) | H: Peptidase inhibitors family I29 (From Topology) | T: Peptidase inhibitors family I29 | F: Inhibitor_I29 | ECOD (1.6) |
B [auth C] | Peptidase_C1 | e3tnxC1 | A: a+b complex topology | X: Cysteine proteinases-like | H: Cysteine proteinases (From Topology) | T: Cysteine proteinases | F: Peptidase_C1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.90.70.10 | Alpha Beta | Alpha-Beta Complex | Cathepsin B | Chain A | CATH (4.3.0) |
B [auth C] | 3.90.70.10 | Alpha Beta | Alpha-Beta Complex | Cathepsin B | Chain A | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A, B [auth C] | PF08246 | Cathepsin propeptide inhibitor domain (I29) (Inhibitor_I29) | Cathepsin propeptide inhibitor domain (I29) | This domain is found at the N-terminus of some C1 peptidases such as Cathepsin L where it acts as a propeptide. There are also a number of proteins that are composed solely of multiple copies of this domain such as the peptidase inhibitor salarin Sw ... | Domain |
A, B [auth C] | PF00112 | Papain family cysteine protease (Peptidase_C1) | Papain family cysteine protease | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|---|---|---|---|
A, B [auth C] | Papain | - |
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A, B [auth C] | IPR038765 | Papain-like cysteine peptidase superfamily | Homologous Superfamily |
A, B [auth C] | IPR025661 | Cysteine peptidase, asparagine active site | Active Site |
A, B [auth C] | IPR000169 | Cysteine peptidase, cysteine active site | Active Site |
A, B [auth C] | IPR025660 | Cysteine peptidase, histidine active site | Active Site |
A, B [auth C] | IPR013128 | Peptidase C1A | Family |
A, B [auth C] | IPR000668 | Peptidase C1A, papain C-terminal | Domain |
A, B [auth C] | IPR013201 | Cathepsin propeptide inhibitor domain (I29) | Domain |
A, B [auth C] | IPR039417 | Papain-like cysteine endopeptidase | Domain |