3TDS

Crystal structure of HSC F194I

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth E]	PF01226	e3tdsE1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF01226	ECOD (1.6)
B [auth A]	PF01226	e3tdsA1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF01226	ECOD (1.6)
E [auth D]	PF01226	e3tdsD1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF01226	ECOD (1.6)
C [auth B]	PF01226	e3tdsB1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF01226	ECOD (1.6)
D [auth C]	PF01226	e3tdsC1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF01226	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth E]	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)
B [auth A]	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)
E [auth D]	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)
C [auth B]	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)
D [auth C]	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth E], B [auth A], C [auth B], D [auth C], E [auth D]	PF01226	Formate/nitrite transporter (Form_Nir_trans)	Formate/nitrite transporter	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth E], B [auth A], C [auth B], D [auth C], E [auth D]	formate/nitrite transporter	cation binding ion binding binding metal ion binding small molecule binding transporter activity transmembrane transporter activity	-	membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth E], B [auth A], C [auth B], D [auth C], E [auth D]	IPR023271	Aquaporin-like	Homologous Superfamily
A [auth E], B [auth A], C [auth B], D [auth C], E [auth D]	IPR024002	Formate/nitrite transporter, conserved site	Conserved Site
A [auth E], B [auth A], C [auth B], D [auth C], E [auth D]	IPR000292	Formate/nitrite transporter	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A [auth E], B [auth A], C [auth B], D [auth C], E [auth D]	OPM	Transmembrane	Alpha-helical polytopic	Major Intrinsic Protein (MIP)/FNT superfamily	Formate/Nitrite transporter (FNT) family

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A [auth E], B [auth A], C [auth B], D [auth C], E [auth D]	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A [auth E], B [auth A], C [auth B], D [auth C], E [auth D]	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A [auth E], B [auth A], C [auth B], D [auth C], E [auth D]	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Channels : Formate/Nitrite Transporter (FNT) Family	FNT3 Hydrosulphide Channel (HSC), pH 9.0

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.