Annotations: 3S2R

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3s2ra_	Small proteins	Iron-sulfur cluster-binding zinc finger CDGSH type	Iron-sulfur cluster-binding zinc finger CDGSH type	automated matches	automated matches	mouse-ear cress,thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
B	d3s2rb1	Small proteins	Iron-sulfur cluster-binding zinc finger CDGSH type	Iron-sulfur cluster-binding zinc finger CDGSH type	automated matches	automated matches	mouse-ear cress,thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
B	d3s2rb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	mouse-ear cress,thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	CISD-like	8059866	3002112	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	CISD-like	8059866	3002112	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	zf-CDGSH_1	e3s2rA2	A: few secondary structure elements	X: CDGSH iron-sulfur domains (From Homology)	H: CDGSH iron-sulfur domains	T: Type 1 and 2	F: zf-CDGSH_1	ECOD (1.6)
B	zf-CDGSH_1	e3s2rB2	A: few secondary structure elements	X: CDGSH iron-sulfur domains (From Homology)	H: CDGSH iron-sulfur domains	T: Type 1 and 2	F: zf-CDGSH_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.5.90	Alpha Beta	3-Layer(aba) Sandwich	Ribosomal Protein L9	domain 1	CATH (4.3.0)
B	3.40.5.90	Alpha Beta	3-Layer(aba) Sandwich	Ribosomal Protein L9	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF09360	Iron-binding zinc finger CDGSH type (zf-CDGSH)	Iron-binding zinc finger CDGSH type	The CDGSH-type zinc finger domain binds iron rather than zinc as a redox-active pH-labile 2Fe-2S cluster. The conserved sequence C-X-C-X2-(S/T)-X3-P-X-C-D-G-(S/A/T)-H is a defining feature of this family [1]. The domain is oriented towards the cytopl ...	The CDGSH-type zinc finger domain binds iron rather than zinc as a redox-active pH-labile 2Fe-2S cluster. The conserved sequence C-X-C-X2-(S/T)-X3-P-X-C-D-G-(S/A/T)-H is a defining feature of this family [1]. The domain is oriented towards the cytoplasm and is tethered to the mitochondrial membrane by a more N-terminal domain found in higher vertebrates, MitoNEET_N, Pfam:PF10660 [2]. The domain forms a uniquely folded homo-dimer and spans the outer mitochondrial membrane, orienting the iron-binding residues towards the cytoplasm [3].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	AT5g51720/MIO24_14	iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding binding metal cluster binding small molecule binding cation binding ion binding metal ion binding	cellular metabolic process reactive oxygen species metabolic process metabolic process cellular process regulation of biological process catabolic process regulation of cellular process biological regulation autophagy regulation of cellular metabolic process regulation of catabolic process regulation of autophagy cellular catabolic process regulation of cellular catabolic process cellular metabolic process reactive oxygen species metabolic process metabolic process cellular process regulation of biological process catabolic process regulation of cellular process biological regulation autophagy regulation of cellular metabolic process regulation of catabolic process regulation of autophagy cellular catabolic process regulation of cellular catabolic process regulation of metabolic process process utilizing autophagic mechanism developmental process multicellular organismal process plant organ development plant organ senescence multicellular organism development anatomical structure development leaf development leaf senescence shoot system development phyllome development system development	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle plastid plastid stroma chloroplast stroma chloroplast cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR018967	Iron-binding zinc finger, CDGSH type	Domain
A, B	IPR045131	CDGSH iron-sulfur domain-containing protein 1/2	Family
A, B	IPR042216	MitoNEET, CDGSH iron-sulfur domain	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.