3S29

The crystal structure of sucrose synthase-1 from Arabidopsis thaliana and its functional implications.

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00862	e3s29A4	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
A	PF00862	e3s29A3	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
A	PF00534	e3s29A2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
A	PF00862	e3s29A1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)
B	PF00862	e3s29B3	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
B	PF00862	e3s29B4	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
B	PF00534	e3s29B1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
B	PF00862	e3s29B2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)
C	PF00862	e3s29C4	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
C	PF00862	e3s29C3	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
C	PF00534	e3s29C2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
C	PF00862	e3s29C1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)
D	PF00862	e3s29D4	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
D	PF00862	e3s29D3	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
D	PF00534	e3s29D2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
D	PF00862	e3s29D1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)
E	PF00862	e3s29E4	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
E	PF00862	e3s29E3	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
E	PF00534	e3s29E2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
E	PF00862	e3s29E1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)
F	PF00862	e3s29F4	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
F	PF00862	e3s29F3	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
F	PF00534	e3s29F2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
F	PF00862	e3s29F1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)
G	PF00862	e3s29G4	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
G	PF00862	e3s29G3	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
G	PF00534	e3s29G2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
G	PF00862	e3s29G1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)
H	PF00862	e3s29H3	A: alpha bundles	X: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	H: ENOD40 peptide-binding domain in sucrose synthase-1 (From Topology)	T: ENOD40 peptide-binding domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
H	PF00862	e3s29H4	A: a+b two layers	X: Cellular targeting domain in sucrose synthase-1 (From Topology)	H: Cellular targeting domain in sucrose synthase-1 (From Topology)	T: Cellular targeting domain in sucrose synthase-1	F: PF00862	ECOD (1.6)
H	PF00534	e3s29H1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00534	ECOD (1.6)
H	PF00862	e3s29H2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: PF00862	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
A	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
A	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
B	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
B	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
B	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
C	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
C	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
C	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
D	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
D	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
D	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
E	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
E	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
E	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
F	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
F	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
F	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
G	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
G	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
G	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
H	3.10.450.330	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
H	1.20.120.1230	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)		CATH (4.3.0)
H	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF00534	Glycosyl transferases group 1 (Glycos_transf_1)	Glycosyl transferases group 1	-	Family
A, B, C, D, E A, B, C, D, E, F, G, H	PF00862	Sucrose synthase (Sucrose_synth)	Sucrose synthase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Sucrose synthase 1	UDP-glycosyltransferase activity glycosyltransferase activity transferase activity glucosyltransferase activity hexosyltransferase activity catalytic activity sucrose synthase activity UDP-glucosyltransferase activity	response to acid chemical response to stimulus response to stress response to chemical response to oxygen-containing compound response to abiotic stimulus response to water response to water deprivation response to inorganic substance sucrose metabolic process carbohydrate metabolic process organic substance metabolic process oligosaccharide metabolic process primary metabolic process response to acid chemical response to stimulus response to stress response to chemical response to oxygen-containing compound response to abiotic stimulus response to water response to water deprivation response to inorganic substance sucrose metabolic process carbohydrate metabolic process organic substance metabolic process oligosaccharide metabolic process primary metabolic process metabolic process disaccharide metabolic process response to cold response to temperature stimulus response to flooding response to decreased oxygen levels response to hypoxia response to oxygen levels cellular response to stimulus cellular response to oxygen levels cellular response to hypoxia cellular response to decreased oxygen levels cellular response to chemical stimulus cellular response to stress cellular process response to organic substance response to carbohydrate response to sorbitol response to hexose response to monosaccharide response to glucose response to osmotic stress response to sucrose response to disaccharide response to mannitol	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol cell-cell junction symplast anchoring junction cell junction plasmodesma

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR001296	Glycosyl transferase, family 1	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR012820	Sucrose synthase, plant/cyanobacteria	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR000368	Sucrose synthase	Domain