3QS9
Crystal structure of a human Flt3 ligand-receptor ternary complex
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | 4-helical cytokines | 8037098 | 3001717 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | 4-helical cytokines | 8037098 | 3001717 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | 4-helical cytokines | 8037098 | 3001717 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | 4-helical cytokines | 8037098 | 3001717 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF02947 | e3qs9A1 | A: alpha bundles | X: Ferritin/Heme oxygenase/4-helical cytokines | H: 4-helical cytokines (From Topology) | T: 4-helical cytokines | F: PF02947 | ECOD (1.6) |
B | PF02947 | e3qs9B1 | A: alpha bundles | X: Ferritin/Heme oxygenase/4-helical cytokines | H: 4-helical cytokines (From Topology) | T: 4-helical cytokines | F: PF02947 | ECOD (1.6) |
C | PF02947 | e3qs9C1 | A: alpha bundles | X: Ferritin/Heme oxygenase/4-helical cytokines | H: 4-helical cytokines (From Topology) | T: 4-helical cytokines | F: PF02947 | ECOD (1.6) |
D | PF02947 | e3qs9D1 | A: alpha bundles | X: Ferritin/Heme oxygenase/4-helical cytokines | H: 4-helical cytokines (From Topology) | T: 4-helical cytokines | F: PF02947 | ECOD (1.6) |
E | F_UNCLASSIFIED | e3qs9E4 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: F_UNCLASSIFIED | ECOD (1.6) |
E | PF00047 | e3qs9E5 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF00047 | ECOD (1.6) |
F | F_UNCLASSIFIED | e3qs9F2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: F_UNCLASSIFIED | ECOD (1.6) |
F | PF00047 | e3qs9F4 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF00047 | ECOD (1.6) |
G | F_UNCLASSIFIED | e3qs9G2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: F_UNCLASSIFIED | ECOD (1.6) |
G | PF00047 | e3qs9G5 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF00047 | ECOD (1.6) |
H | F_UNCLASSIFIED | e3qs9H2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: F_UNCLASSIFIED | ECOD (1.6) |
H | PF00047 | e3qs9H5 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF00047 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF02947 | flt3 ligand (Flt3_lig) | flt3 ligand | The flt3 ligand is a short chain cytokine with a 4 helical bundle fold. | Domain | |
PF00047 | Immunoglobulin domain (ig) | Immunoglobulin domain | Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions. Examples include antibodies, the giant muscle kinase titin and receptor tyrosine kinases. Immunoglobulin-like domains may be involved in protein-prot ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR004213 | Flt3 ligand | Family | |
IPR009079 | Four-helical cytokine-like, core | Homologous Superfamily | |
IPR017441 | Protein kinase, ATP binding site | Binding Site | |
IPR001824 | Tyrosine-protein kinase, receptor class III, conserved site | Conserved Site | |
IPR036179 | Immunoglobulin-like domain superfamily | Homologous Superfamily | |
IPR008266 | Tyrosine-protein kinase, active site | Active Site | |
IPR020635 | Tyrosine-protein kinase, catalytic domain | Domain | |
IPR000719 | Protein kinase domain | Domain | |
IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain | Domain | |
IPR011009 | Protein kinase-like domain superfamily | Homologous Superfamily | |
IPR013783 | Immunoglobulin-like fold | Homologous Superfamily | |
IPR013151 | Immunoglobulin | Domain | |
IPR007110 | Immunoglobulin-like domain | Domain |