3QD9
C72S/C353S mutant of Trypanosoma brucei QSOX containing an interdomain disulfide
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
C | PF04777,PF22220 | e3qd9C5 | A: alpha bundles | X: Four-helical up-and-down bundle | H: FAD-dependent thiol oxidase (From Topology) | T: FAD-dependent thiol oxidase | F: PF04777,PF22220 | ECOD (1.6) |
C | PF00085 | e3qd9C6 | A: a+b three layers | X: Thioredoxin-like | H: Thioredoxin-like (From Topology) | T: Thioredoxin-like | F: PF00085 | ECOD (1.6) |
A | PF04777,PF22220 | e3qd9A5 | A: alpha bundles | X: Four-helical up-and-down bundle | H: FAD-dependent thiol oxidase (From Topology) | T: FAD-dependent thiol oxidase | F: PF04777,PF22220 | ECOD (1.6) |
A | PF00085 | e3qd9A6 | A: a+b three layers | X: Thioredoxin-like | H: Thioredoxin-like (From Topology) | T: Thioredoxin-like | F: PF00085 | ECOD (1.6) |
B | PF04777,PF22220 | e3qd9B5 | A: alpha bundles | X: Four-helical up-and-down bundle | H: FAD-dependent thiol oxidase (From Topology) | T: FAD-dependent thiol oxidase | F: PF04777,PF22220 | ECOD (1.6) |
B | PF00085 | e3qd9B6 | A: a+b three layers | X: Thioredoxin-like | H: Thioredoxin-like (From Topology) | T: Thioredoxin-like | F: PF00085 | ECOD (1.6) |
D | PF04777,PF22220 | e3qd9D1 | A: alpha bundles | X: Four-helical up-and-down bundle | H: FAD-dependent thiol oxidase (From Topology) | T: FAD-dependent thiol oxidase | F: PF04777,PF22220 | ECOD (1.6) |
D | PF00085 | e3qd9D2 | A: a+b three layers | X: Thioredoxin-like | H: Thioredoxin-like (From Topology) | T: Thioredoxin-like | F: PF00085 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
C | 3.40.30.10 | Alpha Beta | 3-Layer(aba) Sandwich | Glutaredoxin | Glutaredoxin | CATH (4.3.0) |
A | 3.40.30.10 | Alpha Beta | 3-Layer(aba) Sandwich | Glutaredoxin | Glutaredoxin | CATH (4.3.0) |
B | 3.40.30.10 | Alpha Beta | 3-Layer(aba) Sandwich | Glutaredoxin | Glutaredoxin | CATH (4.3.0) |
D | 3.40.30.10 | Alpha Beta | 3-Layer(aba) Sandwich | Glutaredoxin | Glutaredoxin | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00085 | Thioredoxin (Thioredoxin) | Thioredoxin | Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond. Some members with only the active site are not separated from the noise. | Domain | |
PF04777 | Erv1 / Alr family (Evr1_Alr) | Erv1 / Alr family | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR036774 | ERV/ALR sulfhydryl oxidase domain superfamily | Homologous Superfamily | |
IPR013766 | Thioredoxin domain | Domain | |
IPR039798 | Sulfhydryl oxidase | Family | |
IPR017937 | Thioredoxin, conserved site | Conserved Site | |
IPR017905 | ERV/ALR sulfhydryl oxidase domain | Domain | |
IPR036249 | Thioredoxin-like superfamily | Homologous Superfamily |