3PIL

Crystal structure of Mxr1 from Saccharomyces cerevisiae in reduced form

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3pila1	Alpha and beta proteins (a+b)	Ferredoxin-like	Peptide methionine sulfoxide reductase	automated matches	automated matches	yeast (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)
A	d3pila2	Artifacts	Tags	Tags	Tags	N-terminal Tags	yeast (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)
B	d3pilb_	Alpha and beta proteins (a+b)	Ferredoxin-like	Peptide methionine sulfoxide reductase	automated matches	automated matches	yeast (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Peptide methionine sulfoxide reductase	8081991	3001262	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Peptide methionine sulfoxide reductase	8081991	3001262	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PMSR	e3pilA1	A: a+b two layers	X: Alpha-beta plaits	H: HMA-related	T: Peptide methionine sulfoxide reductase	F: PMSR	ECOD (1.6)
B	PMSR	e3pilB1	A: a+b two layers	X: Alpha-beta plaits	H: HMA-related	T: Peptide methionine sulfoxide reductase	F: PMSR	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.1060.10	Alpha Beta	2-Layer Sandwich	Peptide Methionine Sulfoxide Reductase	Chain A	CATH (4.3.0)
B	3.30.1060.10	Alpha Beta	2-Layer Sandwich	Peptide Methionine Sulfoxide Reductase	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01625	Peptide methionine sulfoxide reductase (PMSR)	Peptide methionine sulfoxide reductase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Peptide methionine sulfoxide reductase	oxidoreductase activity, acting on a sulfur group of donors oxidoreductase activity oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor L-methionine-(S)-S-oxide reductase activity L-methionine:thioredoxin-disulfide S-oxidoreductase activity catalytic activity peptide-methionine (S)-S-oxide reductase activity	cellular response to stimulus response to oxidative stress cellular response to chemical stimulus response to stimulus cellular response to stress response to stress response to chemical cellular response to oxidative stress cellular process cellular response to chemical stress	intracellular anatomical structure cytoplasm cellular anatomical entity membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR002569	Peptide methionine sulphoxide reductase MsrA domain	Domain
A, B	IPR036509	Peptide methionine sulphoxide reductase MsrA superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.