Annotations: 3OR1

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
C	d3or1c_	Alpha and beta proteins (a+b)	DsrC, the gamma subunit of dissimilatory sulfite reductase	DsrC, the gamma subunit of dissimilatory sulfite reductase	DsrC, the gamma subunit of dissimilatory sulfite reductase	automated matches	(Megalodesulfovibrio gigas ) [TaxId: 879 ],	SCOPe (2.08)
F	d3or1f_	Alpha and beta proteins (a+b)	DsrC, the gamma subunit of dissimilatory sulfite reductase	DsrC, the gamma subunit of dissimilatory sulfite reductase	DsrC, the gamma subunit of dissimilatory sulfite reductase	automated matches	(Megalodesulfovibrio gigas ) [TaxId: 879 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2 Family	DsrC the gamma subunit of dissimilatory sulfite reductase	8081311	4003436	SCOP2 (2022-06-29)
C	SCOP2 Superfamily	DsrC the gamma subunit of dissimilatory sulfite reductase	8081312	3000863	SCOP2 (2022-06-29)
F	SCOP2B Superfamily	DsrC the gamma subunit of dissimilatory sulfite reductase	8081312	3000863	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e3or1A9	A: a+b two layers	X: 4Fe-4S ferredoxin (From Topology)	H: 4Fe-4S ferredoxin (From Topology)	T: 4Fe-4S ferredoxin	F: F_UNCLASSIFIED	ECOD (1.6)
A	F_UNCLASSIFIED	e3or1A1	A: a+b two layers	X: Alpha-beta plaits	H: Sulfite reductase, domains 1 and 3 (From Topology)	T: Sulfite reductase, domains 1 and 3	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF01077	e3or1A8	A: a+b three layers	X: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 (From Topology)	H: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 (From Topology)	T: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4	F: PF01077	ECOD (1.6)
D	F_UNCLASSIFIED	e3or1D2	A: a+b two layers	X: 4Fe-4S ferredoxin (From Topology)	H: 4Fe-4S ferredoxin (From Topology)	T: 4Fe-4S ferredoxin	F: F_UNCLASSIFIED	ECOD (1.6)
D	F_UNCLASSIFIED	e3or1D1	A: a+b two layers	X: Alpha-beta plaits	H: Sulfite reductase, domains 1 and 3 (From Topology)	T: Sulfite reductase, domains 1 and 3	F: F_UNCLASSIFIED	ECOD (1.6)
D	PF01077	e3or1D8	A: a+b three layers	X: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 (From Topology)	H: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 (From Topology)	T: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4	F: PF01077	ECOD (1.6)
B	PF12838	e3or1B8	A: a+b two layers	X: 4Fe-4S ferredoxin (From Topology)	H: 4Fe-4S ferredoxin (From Topology)	T: 4Fe-4S ferredoxin	F: PF12838	ECOD (1.6)
B	PF03460	e3or1B1	A: a+b two layers	X: Alpha-beta plaits	H: Sulfite reductase, domains 1 and 3 (From Topology)	T: Sulfite reductase, domains 1 and 3	F: PF03460	ECOD (1.6)
B	PF01077	e3or1B9	A: a+b three layers	X: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 (From Topology)	H: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 (From Topology)	T: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4	F: PF01077	ECOD (1.6)
E	PF12838	e3or1E8	A: a+b two layers	X: 4Fe-4S ferredoxin (From Topology)	H: 4Fe-4S ferredoxin (From Topology)	T: 4Fe-4S ferredoxin	F: PF12838	ECOD (1.6)
E	PF03460	e3or1E1	A: a+b two layers	X: Alpha-beta plaits	H: Sulfite reductase, domains 1 and 3 (From Topology)	T: Sulfite reductase, domains 1 and 3	F: PF03460	ECOD (1.6)
E	PF01077	e3or1E9	A: a+b three layers	X: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 (From Topology)	H: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 (From Topology)	T: Sulfite reductase hemoprotein (SiRHP), domains 2 and 4	F: PF01077	ECOD (1.6)
C	PF04358	e3or1C1	A: alpha arrays	X: HTH	H: HTH	T: tri-helical	F: PF04358	ECOD (1.6)
F	PF04358	e3or1F1	A: alpha arrays	X: HTH	H: HTH	T: tri-helical	F: PF04358	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	6.10.140.1420	Special	Helix non-globular	Helix Hairpins		CATH (4.3.0)
A	3.30.70.2500	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
A	3.30.413.10	Alpha Beta	2-Layer Sandwich	Sulfite Reductase Hemoprotein	domain 1	CATH (4.3.0)
A	3.30.70.20	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
D	6.10.140.1420	Special	Helix non-globular	Helix Hairpins		CATH (4.3.0)
D	3.30.70.2500	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
D	3.30.413.10	Alpha Beta	2-Layer Sandwich	Sulfite Reductase Hemoprotein	domain 1	CATH (4.3.0)
D	3.30.70.20	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
B	3.30.70.3340	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
B	3.30.413.10	Alpha Beta	2-Layer Sandwich	Sulfite Reductase Hemoprotein	domain 1	CATH (4.3.0)
B	3.30.70.20	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
E	3.30.70.3340	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
E	3.30.413.10	Alpha Beta	2-Layer Sandwich	Sulfite Reductase Hemoprotein	domain 1	CATH (4.3.0)
E	3.30.70.20	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
C	3.30.1420.10	Alpha Beta	2-Layer Sandwich	Dissimilatory Siroheme-sulfite Reductase	Chain: A	CATH (4.3.0)
C	1.10.10.370	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	DsrC protein, C-terminal domain	CATH (4.3.0)
F	3.30.1420.10	Alpha Beta	2-Layer Sandwich	Dissimilatory Siroheme-sulfite Reductase	Chain: A	CATH (4.3.0)
F	1.10.10.370	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	DsrC protein, C-terminal domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, D	PF01077	Nitrite and sulphite reductase 4Fe-4S domain (NIR_SIR)	Nitrite and sulphite reductase 4Fe-4S domain	-	Family
B, E	PF03460	Nitrite/Sulfite reductase ferredoxin-like half domain (NIR_SIR_ferr)	Nitrite/Sulfite reductase ferredoxin-like half domain	-	Repeat
B, E	PF01077	Nitrite and sulphite reductase 4Fe-4S domain (NIR_SIR)	Nitrite and sulphite reductase 4Fe-4S domain	-	Family
B, E	PF12838	4Fe-4S dicluster domain (Fer4_7)	4Fe-4S dicluster domain	Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contai ...	Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.	Domain
C, F	PF04358	DsrC like protein (DsrC)	DsrC like protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, D	Sulfite reductase alpha	oxidoreductase activity, acting on a sulfur group of donors oxidoreductase activity dissimilatory sulfite reductase activity catalytic activity iron-sulfur cluster binding binding 4 iron, 4 sulfur cluster binding metal cluster binding small molecule binding organic cyclic compound binding tetrapyrrole binding heme binding cation binding ion binding oxidoreductase activity, acting on a sulfur group of donors oxidoreductase activity dissimilatory sulfite reductase activity catalytic activity iron-sulfur cluster binding binding 4 iron, 4 sulfur cluster binding metal cluster binding small molecule binding organic cyclic compound binding tetrapyrrole binding heme binding cation binding ion binding metal ion binding	-	-
B, E	Sulfite reductase beta	oxidoreductase activity, acting on a sulfur group of donors oxidoreductase activity dissimilatory sulfite reductase activity catalytic activity binding organic cyclic compound binding tetrapyrrole binding heme binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding metal cluster binding small molecule binding electron transfer activity cation binding oxidoreductase activity, acting on a sulfur group of donors oxidoreductase activity dissimilatory sulfite reductase activity catalytic activity binding organic cyclic compound binding tetrapyrrole binding heme binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding metal cluster binding small molecule binding electron transfer activity cation binding ion binding metal ion binding	cellular metabolic process sulfur compound metabolic process metabolic process cellular process	-
C, F	Sulfite reductase gama	-	-	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, D	IPR006067	Nitrite/sulphite reductase 4Fe-4S domain	Domain
A, D	IPR017896	4Fe-4S ferredoxin-type, iron-sulphur binding domain	Domain
A, D	IPR045854	Nitrite and sulphite reductase 4Fe-4S domain-like superfamily	Homologous Superfamily
A, D	IPR036136	Nitrite/Sulfite reductase ferredoxin-like domain superfamily	Homologous Superfamily
A, D	IPR045169	Nitrite and sulphite reductase 4Fe-4S domain containing protein	Family
A, D	IPR011806	Sulphite reductase, dissimilatory-type alpha subunit	Family
B, E	IPR005117	Nitrite/Sulfite reductase ferredoxin-like domain	Domain
B, E	IPR011808	Sulphite reductase, dissimilatory-type beta subunit	Family
B, E	IPR017900	4Fe-4S ferredoxin, iron-sulphur binding, conserved site	Conserved Site
B, E	IPR006067	Nitrite/sulphite reductase 4Fe-4S domain	Domain
B, E	IPR017896	4Fe-4S ferredoxin-type, iron-sulphur binding domain	Domain
B, E	IPR045854	Nitrite and sulphite reductase 4Fe-4S domain-like superfamily	Homologous Superfamily
B, E	IPR036136	Nitrite/Sulfite reductase ferredoxin-like domain superfamily	Homologous Superfamily
B, E	IPR045169	Nitrite and sulphite reductase 4Fe-4S domain containing protein	Family
C, F	IPR043163	DsrC-like protein, N-terminal domain	Homologous Superfamily
C, F	IPR025526	DsrC-like domain superfamily	Homologous Superfamily
C, F	IPR042072	DsrC-like protein, C-terminal domain	Homologous Superfamily
C, F	IPR007453	Sulphur transfer protein DsrC/TusE	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.