3O7Q

Crystal structure of a Major Facilitator Superfamily (MFS) transporter, FucP, in the outward conformation

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3o7qa_	Membrane and cell surface proteins and peptides	MFS general substrate transporter	MFS general substrate transporter	FucP-like proton/sugar symporter	L-fucose transporter FucP	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e3o7qA6	A: alpha complex topology	X: Major facilitator superfamily (MFS) general substrate transporter (From Topology)	H: Major facilitator superfamily (MFS) general substrate transporter (From Topology)	T: Major facilitator superfamily (MFS) general substrate transporter	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF07690	e3o7qA5	A: alpha complex topology	X: Major facilitator superfamily (MFS) general substrate transporter (From Topology)	H: Major facilitator superfamily (MFS) general substrate transporter (From Topology)	T: Major facilitator superfamily (MFS) general substrate transporter	F: PF07690	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.1250.20	Mainly Alpha	Up-down Bundle	Growth Hormone	Chain: A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00083	Sugar (and other) transporter (Sugar_tr)	Sugar (and other) transporter	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	L-fucose-proton symporter	monoatomic cation transmembrane transporter activity monosaccharide transmembrane transporter activity sugar transmembrane transporter activity proton transmembrane transporter activity solute:monoatomic cation symporter activity arabinose:proton symporter activity pentose transmembrane transporter activity secondary active transmembrane transporter activity carbohydrate:monoatomic cation symporter activity active monoatomic ion transmembrane transporter activity arabinose transmembrane transporter activity carbohydrate:proton symporter activity active transmembrane transporter activity inorganic molecular entity transmembrane transporter activity solute:proton symporter activity monoatomic cation transmembrane transporter activity monosaccharide transmembrane transporter activity sugar transmembrane transporter activity proton transmembrane transporter activity solute:monoatomic cation symporter activity arabinose:proton symporter activity pentose transmembrane transporter activity secondary active transmembrane transporter activity carbohydrate:monoatomic cation symporter activity active monoatomic ion transmembrane transporter activity arabinose transmembrane transporter activity carbohydrate:proton symporter activity active transmembrane transporter activity inorganic molecular entity transmembrane transporter activity solute:proton symporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity carbohydrate transmembrane transporter activity transmembrane transporter activity symporter activity fucose:proton symporter activity hexose:proton symporter activity hexose transmembrane transporter activity fucose transmembrane transporter activity galactose:proton symporter activity galactose transmembrane transporter activity	monosaccharide metabolic process carbohydrate metabolic process organic substance metabolic process hexose metabolic process small molecule metabolic process metabolic process primary metabolic process fucose metabolic process fucose transmembrane transport hexose transmembrane transport transport organic substance transport carbohydrate transport establishment of localization monosaccharide metabolic process carbohydrate metabolic process organic substance metabolic process hexose metabolic process small molecule metabolic process metabolic process primary metabolic process fucose metabolic process fucose transmembrane transport hexose transmembrane transport transport organic substance transport carbohydrate transport establishment of localization transmembrane transport localization cellular process monosaccharide transmembrane transport carbohydrate transmembrane transport arabinose transmembrane transport pentose transmembrane transport galactose transmembrane transport	membrane cellular anatomical entity cell periphery plasma membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR011701	Major facilitator superfamily	Family
A	IPR036259	MFS transporter superfamily	Homologous Superfamily
A	IPR020846	Major facilitator superfamily domain	Domain
A	IPR005275	L-fucose-proton symporter FucP	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A	OPM	Transmembrane	Alpha-helical polytopic	Major Facilitator Superfamily (MFS)	Fucose-proton symporter

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Major Facilitator Superfamily (MFS) Transporters	FucP Fucose Transporter in outward-facing conformation

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.