3O4X

Crystal structure of complex between amino and carboxy terminal fragments of mDia1

External Resource: Annotation


Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyARM repeat-like8038395 3000116 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyARM repeat-like8038395 3000116 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyARM repeat-like8038395 3000116 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyARM repeat-like8038395 3000116 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyFormin homology 2 domain (FH2 domain)8035646 3001266 SCOP2B (2022-06-29)
F [auth H]SCOP2B SuperfamilyFormin homology 2 domain (FH2 domain)8035646 3001266 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyFormin homology 2 domain (FH2 domain)8035646 3001266 SCOP2B (2022-06-29)
H [auth F]SCOP2B SuperfamilyFormin homology 2 domain (FH2 domain)8035646 3001266 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APF06367,PF06371e3o4xA1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF06367,PF06371ECOD (1.6)
CPF06367,PF06371e3o4xC1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF06367,PF06371ECOD (1.6)
DPF06367,PF06371e3o4xD1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF06367,PF06371ECOD (1.6)
BPF06367,PF06371e3o4xB1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF06367,PF06371ECOD (1.6)
EPF02181,PF06345e3o4xE1 A: alpha complex topologyX: Formin homology 2 domain (FH2 domain) (From Topology)H: Formin homology 2 domain (FH2 domain) (From Topology)T: Formin homology 2 domain (FH2 domain)F: PF02181,PF06345ECOD (1.6)
F [auth H]PF02181e3o4xH1 A: alpha complex topologyX: Formin homology 2 domain (FH2 domain) (From Topology)H: Formin homology 2 domain (FH2 domain) (From Topology)T: Formin homology 2 domain (FH2 domain)F: PF02181ECOD (1.6)
GPF02181,PF06345e3o4xG1 A: alpha complex topologyX: Formin homology 2 domain (FH2 domain) (From Topology)H: Formin homology 2 domain (FH2 domain) (From Topology)T: Formin homology 2 domain (FH2 domain)F: PF02181,PF06345ECOD (1.6)
H [auth F]PF02181,PF06345e3o4xF1 A: alpha complex topologyX: Formin homology 2 domain (FH2 domain) (From Topology)H: Formin homology 2 domain (FH2 domain) (From Topology)T: Formin homology 2 domain (FH2 domain)F: PF02181,PF06345ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A1.25.10.10 Mainly Alpha Alpha Horseshoe Leucine-rich Repeat Variant Leucine-rich Repeat VariantCATH (4.3.0)
A1.10.238.150 Mainly Alpha Orthogonal Bundle Recoverin domain 1CATH (4.3.0)
C1.25.10.10 Mainly Alpha Alpha Horseshoe Leucine-rich Repeat Variant Leucine-rich Repeat VariantCATH (4.3.0)
C1.10.238.150 Mainly Alpha Orthogonal Bundle Recoverin domain 1CATH (4.3.0)
D1.25.10.10 Mainly Alpha Alpha Horseshoe Leucine-rich Repeat Variant Leucine-rich Repeat VariantCATH (4.3.0)
D1.10.238.150 Mainly Alpha Orthogonal Bundle Recoverin domain 1CATH (4.3.0)
B1.25.10.10 Mainly Alpha Alpha Horseshoe Leucine-rich Repeat Variant Leucine-rich Repeat VariantCATH (4.3.0)
B1.10.238.150 Mainly Alpha Orthogonal Bundle Recoverin domain 1CATH (4.3.0)
E6.10.30.30 Special Helix non-globular Lyase 2-enoyl-coa Hydratase Chain A, domain 2CATH (4.3.0)
E1.20.58.630 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase Chain G, domain 1CATH (4.3.0)
E1.20.58.2220 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase Chain G, domain 1CATH (4.3.0)
F [auth H]6.10.30.30 Special Helix non-globular Lyase 2-enoyl-coa Hydratase Chain A, domain 2CATH (4.3.0)
F [auth H]1.20.58.630 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase Chain G, domain 1CATH (4.3.0)
F [auth H]1.20.58.2220 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase Chain G, domain 1CATH (4.3.0)
G6.10.30.30 Special Helix non-globular Lyase 2-enoyl-coa Hydratase Chain A, domain 2CATH (4.3.0)
G1.20.58.630 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase Chain G, domain 1CATH (4.3.0)
G1.20.58.2220 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase Chain G, domain 1CATH (4.3.0)
H [auth F]6.10.30.30 Special Helix non-globular Lyase 2-enoyl-coa Hydratase Chain A, domain 2CATH (4.3.0)
H [auth F]1.20.58.630 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase Chain G, domain 1CATH (4.3.0)
H [auth F]1.20.58.2220 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase Chain G, domain 1CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF06371Diaphanous GTPase-binding Domain (Drf_GBD)Diaphanous GTPase-binding Domain- Repeat
A, B, C, D
PF06367Diaphanous FH3 Domain (Drf_FH3)Diaphanous FH3 Domain- Repeat
E,
F [auth H],
G,
H [auth F]		PF02181Formin Homology 2 Domain (FH2)Formin Homology 2 Domain- Family
E,
F [auth H],
G,
H [auth F]		PF06346Formin Homology Region 1 (Drf_FH1)Formin Homology Region 1- Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D
Protein diaphanous homolog 1
E,
F [auth H],
G,
H [auth F]		Protein diaphanous homolog 1

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D
IPR042201Formin, FH2 domain superfamilyHomologous Superfamily
A, B, C, D
IPR016024Armadillo-type foldHomologous Superfamily
A, B, C, D
IPR015425Formin, FH2 domainDomain
A, B, C, D
IPR011989Armadillo-like helicalHomologous Superfamily
A, B, C, D
IPR014767Diaphanous autoregulatory (DAD) domainDomain
A, B, C, D
IPR010472Formin, FH3 domainDomain
A, B, C, D
IPR010473Formin, GTPase-binding domainDomain
A, B, C, D
IPR014768Rho GTPase-binding/formin homology 3 (GBD/FH3) domainDomain
A, B, C, D
IPR044933Diaphanous, GTPase-binding domain superfamilyHomologous Superfamily
E,
F [auth H],
G,
H [auth F]		IPR042201Formin, FH2 domain superfamilyHomologous Superfamily
E,
F [auth H],
G,
H [auth F]		IPR016024Armadillo-type foldHomologous Superfamily
E,
F [auth H],
G,
H [auth F]		IPR015425Formin, FH2 domainDomain
E,
F [auth H],
G,
H [auth F]		IPR011989Armadillo-like helicalHomologous Superfamily
E,
F [auth H],
G,
H [auth F]		IPR014767Diaphanous autoregulatory (DAD) domainDomain
E,
F [auth H],
G,
H [auth F]		IPR010472Formin, FH3 domainDomain
E,
F [auth H],
G,
H [auth F]		IPR010473Formin, GTPase-binding domainDomain
E,
F [auth H],
G,
H [auth F]		IPR014768Rho GTPase-binding/formin homology 3 (GBD/FH3) domainDomain
E,
F [auth H],
G,
H [auth F]		IPR044933Diaphanous, GTPase-binding domain superfamilyHomologous Superfamily